| Player | Team | IP | K | BB | ERA | WHIP | FIP | ERA+ |
|---|---|---|---|---|---|---|---|---|
| Garrett Acton | Rays | 1.0 | 0 | 2 | 0.00 | 2.00 | 9.10 | |
| Tomás Nido | Tigers | 1.7 | 0 | 0 | 0.00 | 0.00 | 3.10 | |
| Casey Kelly | Diamondbacks | 1.2 | 0 | 1 | 0.00 | 1.20 | 5.60 | |
| Christian Roa | Marlins | 3.0 | 3 | 3 | 0.00 | 1.33 | 4.10 | |
| Alex Lange | Tigers | 1.0 | 1 | 1 | 0.00 | 3.00 | 4.10 | |
| Leo Rivas | Mariners | 1.0 | 0 | 1 | 0.00 | 4.00 | 6.10 | |
| Nick Raquet | Cardinals | 2.0 | 1 | 1 | 0.00 | 0.50 | 3.60 | |
| Jose Espada | Orioles | 3.0 | 4 | 0 | 0.00 | 0.33 | 0.43 | |
| Ezequiel Duran | Rangers | 3.1 | 0 | 0 | 0.00 | 0.30 | 3.10 | |
| Carl Edwards Jr. | Rangers | 3.0 | 4 | 2 | 0.00 | 0.67 | 2.43 | |
| Alec Burleson | Cardinals | 1.0 | 0 | 0 | 0.00 | 1.00 | 3.10 | |
| Logan Davidson | Athletics | 1.0 | 1 | 0 | 0.00 | 0.00 | 1.10 | |
| Alan Trejo | Rockies | 1.0 | 0 | 0 | 0.00 | 1.00 | 3.10 | |
| Garrett Hampson | Cardinals | 1.0 | 0 | 0 | 0.00 | 0.00 | 3.10 | |
| Christian Koss | Giants | 4.0 | 0 | 0 | 0.00 | 1.00 | 3.10 | |
| Zach Thompson | Braves | 3.7 | 3 | 1 | 0.00 | 0.27 | 2.28 | |
| Weston Wilson | Phillies | 3.0 | 0 | 0 | 0.00 | 1.00 | 3.10 | |
| Luke Maile | Royals | 1.0 | 0 | 1 | 0.00 | 1.00 | 6.10 | |
| Reiver Sanmartin | Reds | 1.2 | 2 | 1 | 0.00 | 1.80 | 2.27 | |
| Luis Vázquez | Orioles | 4.1 | 0 | 1 | 0.00 | 0.92 | 3.83 | |
| Jared Triolo | Pirates | 1.0 | 0 | 1 | 0.00 | 4.00 | 19.10 | |
| Michael Fulmer | Cubs | 3.0 | 1 | 0 | 0.00 | 0.67 | 2.43 | |
| César Salazar | Astros | 1.0 | 0 | 0 | 0.00 | 0.00 | 3.10 | |
| Jacob Amaya | White Sox | 1.0 | 0 | 0 | 0.00 | 0.00 | 3.10 | |
| Christian Montes De Oca | Diamondbacks | 2.2 | 2 | 1 | 0.00 | 0.38 | 2.65 | |
| Austin Warren | Mets | 9.3 | 9 | 4 | 0.00 | 0.96 | 3.85 | |
| Nate Eaton | Red Sox | 1.0 | 0 | 0 | 0.00 | 2.00 | 3.10 | |
| Nick Burdi | Red Sox | 5.1 | 5 | 2 | 0.00 | 1.31 | 2.32 | |
| Austin Pope | Diamondbacks | 2.0 | 1 | 1 | 0.00 | 1.50 | 3.60 | |
| Niko Kavadas | Angels | 1.2 | 1 | 1 | 0.00 | 2.40 | 3.93 | |
| Hunter Barco | Pirates | 3.0 | 3 | 0 | 0.00 | 1.00 | 1.10 | |
| Hunter Harvey | Royals | 10.7 | 11 | 1 | 0.00 | 0.66 | 1.32 | |
| Ryan Burr | Blue Jays | 2.0 | 3 | 1 | 0.00 | 1.00 | 1.60 | |
| Evan Phillips | Dodgers | 5.7 | 6 | 2 | 0.00 | 1.06 | 2.04 | |
| Jhonathan Díaz | Mariners | 1.1 | 1 | 0 | 0.00 | 0.75 | 1.28 | |
| Justin Lawrence | Pirates | 17.7 | 23 | 8 | 0.00 | 0.96 | 1.85 | |
| Ryan Fitzgerald | Twins | 2.0 | 0 | 0 | 0.00 | 1.00 | 3.10 | |
| Willie MacIver | Athletics | 2.0 | 0 | 0 | 0.00 | 2.00 | 3.10 | |
| José Quijada | Angels | 1.1 | 3 | 2 | 0.00 | 2.25 | 3.10 | |
| Willi Castro | Twins | 1.0 | 0 | 0 | 0.00 | 1.00 | 3.10 | |
| Adam Ottavino | Yankees | 1.7 | 3 | 4 | 0.00 | 2.40 | 6.69 | |
| Dom Hamel | Mets | 1.0 | 0 | 0 | 0.00 | 3.00 | 3.10 | |
| Miles Mastrobuoni | Mariners | 1.0 | 0 | 2 | 0.00 | 3.00 | 9.10 | |
| Anthony Seigler | Brewers | 1.0 | 0 | 0 | 0.00 | 1.00 | 3.10 | |
| Michael Stefanic | Blue Jays | 1.0 | 0 | 0 | 0.00 | 0.00 | 3.10 | |
| Ron Marinaccio | Padres | 10.2 | 12 | 4 | 0.84 | 0.94 | 1.92 | 500 |
| A.J. Minter | Mets | 11.0 | 14 | 5 | 1.00 | 1.00 | 1.92 | 420 |
| José Suarez | Braves | 19.3 | 16 | 10 | 1.00 | 1.29 | 3.67 | 420 |
| Abner Uribe | Brewers | 75.3 | 90 | 27 | 1.00 | 1.04 | 2.48 | 420 |
| Jayden Murray | Astros | 11.7 | 8 | 3 | 1.00 | 1.11 | 2.50 | 420 |
| Paul Skenes | Pirates | 187.7 | 216 | 42 | 1.00 | 0.95 | 2.23 | 420 |
| Luinder Avila | Royals | 14.0 | 16 | 6 | 1.00 | 0.93 | 2.10 | 420 |
| AJ Blubaugh | Astros | 32.0 | 35 | 11 | 1.00 | 0.88 | 4.38 | 420 |
| Bailey Horn | Tigers | 11.3 | 10 | 7 | 1.00 | 1.59 | 4.34 | 420 |
| Dylan Smith | Tigers | 13.0 | 4 | 5 | 1.00 | 0.85 | 3.64 | 420 |
| Logan Henderson | Brewers | 25.3 | 33 | 8 | 1.00 | 0.99 | 2.98 | 420 |
| Edwin Díaz | Mets | 66.3 | 98 | 21 | 1.00 | 0.87 | 1.88 | 420 |
| Tyler Rogers | Mets | 77.3 | 48 | 7 | 1.00 | 0.94 | 2.80 | 420 |
| Danny Coulombe | Twins | 31.0 | 31 | 9 | 1.16 | 0.97 | 1.97 | 362 |
| Bradgley Rodriguez | Padres | 7.2 | 9 | 3 | 1.17 | 0.91 | 1.85 | 359 |
| Aroldis Chapman | Red Sox | 61.1 | 85 | 15 | 1.17 | 0.70 | 1.69 | 359 |
| Cody Laweryson | Twins | 7.2 | 7 | 0 | 1.17 | 0.52 | 1.16 | 359 |
| Andrew Saalfrank | Diamondbacks | 29.0 | 19 | 10 | 1.24 | 1.00 | 3.27 | 339 |
| Cristian Mena | Diamondbacks | 6.2 | 8 | 3 | 1.35 | 0.90 | 4.07 | 311 |
| Erik Miller | Giants | 30.0 | 22 | 20 | 1.50 | 1.47 | 3.63 | 280 |
| Cole Winn | Rangers | 41.2 | 35 | 17 | 1.51 | 0.96 | 3.59 | 278 |
| Chase Silseth | Angels | 11.0 | 13 | 6 | 1.64 | 1.45 | 3.55 | 256 |
| Randy Dobnak | Twins | 5.1 | 1 | 2 | 1.69 | 0.75 | 6.43 | 249 |
| Darren McCaughan | Twins | 5.1 | 6 | 1 | 1.69 | 1.13 | 1.34 | 249 |
| Kade Strowd | Orioles | 26.1 | 24 | 13 | 1.71 | 1.10 | 3.25 | 246 |
| Andrés Muñoz | Mariners | 62.1 | 83 | 28 | 1.73 | 1.03 | 2.20 | 243 |
| Nathan Eovaldi | Rangers | 130.0 | 129 | 21 | 1.73 | 0.85 | 2.60 | 243 |
| Randy Rodríguez | Giants | 50.2 | 67 | 11 | 1.78 | 0.89 | 2.12 | 236 |
| Trevor McDonald | Giants | 15.0 | 14 | 2 | 1.80 | 1.00 | 2.50 | 233 |
| Trevor Rogers | Orioles | 109.2 | 103 | 29 | 1.81 | 0.90 | 2.72 | 232 |
| Erik Sabrowski | Guardians | 29.1 | 42 | 21 | 1.84 | 1.19 | 3.27 | 228 |
| Jason Adam | Padres | 65.1 | 70 | 25 | 1.93 | 1.15 | 2.90 | 218 |
| Matt Svanson | Cardinals | 60.1 | 68 | 20 | 1.94 | 0.88 | 2.48 | 216 |
| Tommy Nance | Blue Jays | 31.2 | 32 | 7 | 1.99 | 1.01 | 1.72 | 211 |
| Cole Sulser | Rays | 22.2 | 22 | 7 | 1.99 | 1.19 | 2.65 | 211 |
| Tyler Phillips | Marlins | 77.7 | 52 | 24 | 2.00 | 1.15 | 4.03 | 210 |
| Hurston Waldrep | Braves | 56.3 | 55 | 22 | 2.00 | 1.19 | 3.01 | 210 |
| Brady Basso | Athletics | 11.7 | 8 | 9 | 2.00 | 1.80 | 4.04 | 210 |
| Edgardo Henriquez | Dodgers | 19.0 | 18 | 5 | 2.00 | 1.16 | 3.36 | 210 |
| Cam Schlittler | Yankees | 73.0 | 84 | 31 | 2.00 | 1.22 | 3.50 | 210 |
| Hunter Brown | Astros | 185.3 | 206 | 57 | 2.00 | 1.03 | 2.99 | 210 |
| Mason Miller | Athletics | 61.7 | 104 | 28 | 2.00 | 0.91 | 2.14 | 210 |
| Anthony Bender | Marlins | 50.0 | 42 | 21 | 2.00 | 1.06 | 3.46 | 210 |
| Jake Rogers | Tigers | 3.7 | 0 | 0 | 2.00 | 1.36 | 3.10 | 210 |
| Will Klein | Dodgers | 15.3 | 21 | 10 | 2.00 | 1.57 | 2.32 | 210 |
| Andrew Chafin | Nationals | 33.7 | 36 | 19 | 2.00 | 1.43 | 3.43 | 210 |
| Matt Strahm | Phillies | 62.3 | 70 | 20 | 2.00 | 1.07 | 2.86 | 210 |
| Chris Devenski | Mets | 16.7 | 14 | 5 | 2.00 | 0.90 | 3.10 | 210 |
| Emmet Sheehan | Dodgers | 73.3 | 89 | 22 | 2.00 | 0.97 | 2.81 | 210 |
| Carlos Estévez | Royals | 66.0 | 54 | 22 | 2.00 | 1.06 | 3.45 | 210 |
| Josh Hader | Astros | 52.7 | 76 | 16 | 2.00 | 0.85 | 3.10 | 210 |
| Tarik Skubal | Tigers | 195.3 | 241 | 33 | 2.00 | 0.89 | 2.34 | 210 |
| Max Fried | Yankees | 195.3 | 189 | 51 | 2.00 | 1.10 | 2.88 | 210 |
| Lucas Erceg | Royals | 61.3 | 48 | 18 | 2.00 | 1.17 | 3.26 | 210 |
| Blake Snell | Dodgers | 61.3 | 72 | 26 | 2.00 | 1.26 | 2.66 | 210 |
| Bryan Abreu | Astros | 71.0 | 105 | 31 | 2.00 | 1.15 | 2.18 | 210 |
| Braxton Ashcraft | Pirates | 69.7 | 71 | 24 | 2.00 | 1.25 | 2.66 | 210 |
| Freddy Peralta | Brewers | 176.7 | 204 | 66 | 2.00 | 1.08 | 3.46 | 210 |
| Aaron Ashby | Brewers | 66.7 | 76 | 24 | 2.00 | 1.17 | 2.49 | 210 |
| Isaac Mattson | Pirates | 47.7 | 45 | 19 | 2.00 | 1.13 | 3.50 | 210 |
| Rob Zastryzny | Brewers | 22.0 | 20 | 10 | 2.00 | 1.18 | 4.42 | 210 |
| Michael Kopech | Dodgers | 11.0 | 12 | 13 | 2.00 | 1.73 | 4.46 | 210 |
| Brooks Raley | Mets | 25.7 | 25 | 6 | 2.00 | 0.78 | 1.85 | 210 |
| Zack Wheeler | Phillies | 149.7 | 195 | 33 | 2.00 | 0.94 | 2.81 | 210 |
| Shohei Ohtani | Dodgers | 47.0 | 62 | 9 | 2.00 | 1.04 | 1.87 | 210 |
| Dennis Santana | Pirates | 70.3 | 60 | 17 | 2.00 | 0.87 | 3.04 | 210 |
| Chris Sale | Braves | 125.7 | 165 | 32 | 2.00 | 1.07 | 2.38 | 210 |
| Cristopher Sánchez | Phillies | 202.0 | 212 | 44 | 2.00 | 1.06 | 2.43 | 210 |
| Yoshinobu Yamamoto | Dodgers | 173.7 | 201 | 59 | 2.00 | 0.99 | 2.85 | 210 |
| Dan Altavilla | White Sox | 29.0 | 21 | 15 | 2.00 | 1.17 | 5.00 | 210 |
| Kevin Herget | Mets | 13.0 | 6 | 5 | 2.00 | 1.31 | 3.33 | 210 |
| Cade Gibson | Marlins | 54.7 | 43 | 21 | 2.00 | 1.19 | 3.39 | 210 |
| Ronny Henriquez | Marlins | 73.0 | 98 | 27 | 2.00 | 1.10 | 2.95 | 210 |
| Bryan King | Astros | 68.0 | 69 | 11 | 2.00 | 1.04 | 3.47 | 210 |
| Mike Vasil | White Sox | 101.0 | 82 | 52 | 2.00 | 1.25 | 4.05 | 210 |
| Craig Kimbrel | Astros | 12.0 | 17 | 7 | 2.00 | 1.42 | 4.18 | 210 |
| Trevor Megill | Brewers | 47.0 | 60 | 17 | 2.00 | 1.13 | 2.46 | 210 |
| Brant Hurter | Tigers | 63.0 | 68 | 27 | 2.00 | 1.33 | 3.05 | 210 |
| Sean Newcomb | Athletics | 92.3 | 91 | 31 | 2.00 | 1.35 | 2.84 | 210 |
| Jhoan Duran | Phillies | 70.0 | 80 | 19 | 2.00 | 1.10 | 2.19 | 210 |
| Wikelman González | White Sox | 20.3 | 25 | 12 | 2.00 | 1.23 | 3.05 | 210 |
| Troy Melton | Tigers | 45.7 | 36 | 15 | 2.00 | 1.01 | 4.50 | 210 |
| Andrew Alvarez | Nationals | 23.3 | 20 | 10 | 2.00 | 1.11 | 3.23 | 210 |
| Brock Stewart | Dodgers | 37.7 | 44 | 13 | 2.00 | 1.19 | 2.83 | 210 |
| Shelby Miller | Brewers | 46.0 | 54 | 15 | 2.00 | 1.04 | 3.14 | 210 |
| J.P. France | Astros | 4.0 | 5 | 2 | 2.00 | 1.00 | 2.10 | 210 |
| Jared Koenig | Brewers | 66.0 | 68 | 20 | 2.00 | 1.17 | 3.13 | 210 |
| Alan Rangel | Phillies | 11.0 | 8 | 6 | 2.00 | 1.45 | 4.46 | 210 |
| Nolan McLean | Mets | 48.0 | 57 | 16 | 2.00 | 1.04 | 2.81 | 210 |
| David Bednar | Pirates | 62.7 | 86 | 19 | 2.00 | 1.04 | 2.09 | 210 |
| Jack Dreyer | Dodgers | 76.3 | 74 | 24 | 2.00 | 1.05 | 2.79 | 210 |
| Noah Cameron | Royals | 138.3 | 114 | 43 | 2.00 | 1.10 | 4.08 | 210 |
| Kris Bubic | Royals | 116.3 | 116 | 39 | 2.00 | 1.18 | 2.78 | 210 |
| Freddy Tarnok | Marlins | 7.3 | 10 | 4 | 2.00 | 0.68 | 3.78 | 210 |
| Bennett Sousa | Astros | 50.7 | 59 | 15 | 2.00 | 1.03 | 2.69 | 210 |
| Louis Varland | Twins | 49.0 | 47 | 13 | 2.02 | 1.10 | 2.77 | 208 |
| Nic Enright | Guardians | 31.0 | 30 | 12 | 2.03 | 1.16 | 3.58 | 207 |
| Riley O'Brien | Cardinals | 48.0 | 45 | 22 | 2.06 | 1.15 | 3.14 | 204 |
| Brad Keller | Cubs | 69.2 | 75 | 22 | 2.07 | 0.96 | 2.64 | 203 |
| JoJo Romero | Cardinals | 61.0 | 55 | 29 | 2.07 | 1.25 | 3.15 | 203 |
| Adrian Morejon | Padres | 73.2 | 70 | 17 | 2.08 | 0.90 | 2.24 | 202 |
| Manuel Rodríguez | Rays | 30.1 | 25 | 6 | 2.08 | 1.05 | 2.90 | 202 |
| Joey Gerber | Rays | 4.1 | 4 | 0 | 2.08 | 0.69 | 4.32 | 202 |
| Drew Pomeranz | Cubs | 49.2 | 57 | 15 | 2.17 | 1.07 | 3.02 | 194 |
| Tyler Mahle | Rangers | 86.2 | 66 | 29 | 2.18 | 1.13 | 3.33 | 193 |
| Nick Sandlin | Blue Jays | 16.1 | 16 | 8 | 2.20 | 1.16 | 4.22 | 191 |
| Garrett Whitlock | Red Sox | 72.0 | 91 | 24 | 2.25 | 1.08 | 1.93 | 187 |
| Tom Cosgrove | Cubs | 4.0 | 3 | 1 | 2.25 | 1.00 | 2.35 | 187 |
| Shawn Armstrong | Rangers | 74.0 | 74 | 20 | 2.31 | 0.81 | 2.79 | 182 |
| Albert Suárez | Orioles | 11.2 | 10 | 2 | 2.31 | 0.94 | 1.85 | 182 |
| Connelly Early | Red Sox | 19.1 | 29 | 4 | 2.33 | 1.09 | 0.69 | 180 |
| Garrett Cleavinger | Rays | 61.1 | 82 | 18 | 2.35 | 0.95 | 3.21 | 179 |
| Joe Rock | Rays | 7.2 | 11 | 2 | 2.35 | 1.17 | 2.68 | 179 |
| Hunter Bigge | Rays | 15.0 | 12 | 5 | 2.40 | 1.07 | 5.97 | 175 |
| Joel Peguero | Giants | 22.1 | 17 | 8 | 2.42 | 1.03 | 3.82 | 174 |
| Tony Santillan | Reds | 73.2 | 75 | 29 | 2.44 | 1.11 | 3.48 | 172 |
| Erasmo Ramírez | Twins | 11.0 | 5 | 2 | 2.45 | 1.09 | 5.10 | 171 |
| Taylor Rogers | Reds | 33.0 | 34 | 19 | 2.45 | 1.45 | 3.95 | 171 |
| Matt Brash | Mariners | 47.1 | 58 | 18 | 2.47 | 1.25 | 2.89 | 170 |
| Jimmy Herget | Rockies | 83.1 | 81 | 26 | 2.48 | 1.18 | 3.03 | 169 |
| Eduard Bazardo | Mariners | 78.2 | 82 | 27 | 2.52 | 1.02 | 3.53 | 167 |
| Kyle Bradish | Orioles | 32.0 | 47 | 10 | 2.53 | 1.03 | 2.32 | 166 |
| Logan Gillaspie | Padres | 7.0 | 4 | 4 | 2.57 | 1.57 | 5.53 | 163 |
| Garrett Crochet | Red Sox | 205.1 | 255 | 46 | 2.59 | 1.03 | 2.81 | 162 |
| Kenley Jansen | Angels | 59.0 | 57 | 19 | 2.59 | 0.95 | 3.90 | 162 |
| Félix Bautista | Orioles | 34.2 | 50 | 23 | 2.60 | 1.13 | 3.33 | 162 |
| Gabe Speier | Mariners | 62.0 | 82 | 11 | 2.61 | 0.87 | 2.04 | 161 |
| Kolby Allard | Guardians | 65.0 | 42 | 14 | 2.63 | 1.20 | 3.45 | 160 |
| Caleb Thielbar | Cubs | 58.0 | 56 | 13 | 2.64 | 0.88 | 2.96 | 159 |
| David Morgan | Padres | 47.1 | 50 | 23 | 2.66 | 1.23 | 3.55 | 158 |
| Corbin Burnes | Diamondbacks | 64.1 | 63 | 26 | 2.66 | 1.17 | 3.77 | 158 |
| Cade Horton | Cubs | 118.0 | 97 | 33 | 2.67 | 1.08 | 3.40 | 157 |
| Braydon Fisher | Blue Jays | 50.0 | 62 | 19 | 2.70 | 1.02 | 2.80 | 156 |
| Robert Stephenson | Angels | 10.0 | 10 | 3 | 2.70 | 1.00 | 3.30 | 156 |
| Parker Messick | Guardians | 39.2 | 38 | 6 | 2.72 | 1.31 | 2.95 | 154 |
| Pablo López | Twins | 75.2 | 73 | 20 | 2.74 | 1.11 | 2.99 | 153 |
| Hunter Greene | Reds | 107.2 | 132 | 26 | 2.76 | 0.94 | 3.18 | 152 |
| Drew Rasmussen | Rays | 150.0 | 127 | 37 | 2.76 | 1.02 | 3.71 | 152 |
| Greg Weissert | Red Sox | 67.0 | 57 | 21 | 2.82 | 1.16 | 3.50 | 149 |
| Pete Fairbanks | Rays | 60.1 | 59 | 18 | 2.83 | 1.04 | 3.55 | 148 |
| Jacob Latz | Rangers | 85.2 | 76 | 37 | 2.84 | 1.24 | 3.69 | 148 |
| Nick Pivetta | Padres | 181.2 | 190 | 50 | 2.87 | 0.99 | 3.41 | 146 |
| Andrew Abbott | Reds | 166.1 | 149 | 43 | 2.87 | 1.15 | 3.57 | 146 |
| Emilio Pagán | Reds | 68.2 | 81 | 22 | 2.88 | 0.92 | 3.60 | 146 |
| Connor Phillips | Reds | 25.0 | 32 | 12 | 2.88 | 0.92 | 3.54 | 146 |
| Tyler Wells | Orioles | 21.2 | 18 | 2 | 2.91 | 0.88 | 4.14 | 144 |
| Daniel Palencia | Cubs | 52.2 | 61 | 16 | 2.91 | 1.14 | 2.93 | 144 |
| Cade Smith | Guardians | 73.2 | 104 | 19 | 2.93 | 1.00 | 1.75 | 143 |
| Bryan Woo | Mariners | 186.2 | 198 | 36 | 2.94 | 0.93 | 3.37 | 143 |
| Robert Garcia | Rangers | 64.0 | 68 | 22 | 2.95 | 1.25 | 3.63 | 142 |
| Jacob deGrom | Rangers | 172.2 | 185 | 37 | 2.97 | 0.92 | 3.56 | 141 |
| Robert Suarez | Padres | 69.2 | 75 | 16 | 2.97 | 0.90 | 2.75 | 141 |
| Jakob Junis | Guardians | 66.2 | 55 | 18 | 2.97 | 1.23 | 3.24 | 141 |
| Chris Martin | Rangers | 42.1 | 43 | 8 | 2.98 | 1.20 | 3.48 | 141 |
| Shane Smith | White Sox | 146.3 | 145 | 58 | 3.00 | 1.20 | 3.82 | 140 |
| Griffin Canning | Mets | 76.3 | 70 | 35 | 3.00 | 1.38 | 4.00 | 140 |
| Jonathan Bowlan | Royals | 44.3 | 46 | 17 | 3.00 | 1.22 | 3.93 | 140 |
| Brandon Walter | Astros | 53.7 | 52 | 4 | 3.00 | 0.93 | 3.81 | 140 |
| Jacob Webb | Rangers | 66.0 | 58 | 19 | 3.00 | 1.03 | 4.18 | 140 |
| José Buttó | Mets | 67.0 | 58 | 32 | 3.00 | 1.40 | 3.58 | 140 |
| Clarke Schmidt | Yankees | 78.7 | 73 | 30 | 3.00 | 1.09 | 3.88 | 140 |
| Matt Gage | Tigers | 31.0 | 27 | 12 | 3.00 | 1.52 | 2.52 | 140 |
| Caleb Ferguson | Pirates | 65.3 | 51 | 22 | 3.00 | 1.16 | 2.95 | 140 |
| Spencer Schwellenbach | Braves | 110.7 | 108 | 18 | 3.00 | 0.97 | 3.16 | 140 |
| Reed Garrett | Mets | 55.3 | 64 | 26 | 3.00 | 1.32 | 3.37 | 140 |
| José Castillo | Mets | 32.0 | 30 | 14 | 3.00 | 1.69 | 4.16 | 140 |
| Alex Vesia | Dodgers | 59.7 | 80 | 22 | 3.00 | 0.99 | 3.49 | 140 |
| PJ Poulin | Nationals | 24.7 | 27 | 13 | 3.00 | 1.46 | 3.55 | 140 |
| Calvin Faucher | Marlins | 60.3 | 59 | 24 | 3.00 | 1.28 | 4.06 | 140 |
| Evan Sisk | Pirates | 17.7 | 25 | 10 | 3.00 | 1.47 | 2.70 | 140 |
| Reese Olson | Tigers | 68.7 | 65 | 25 | 3.00 | 1.21 | 3.25 | 140 |
| Luis Garcia | Astros | 7.7 | 7 | 1 | 3.00 | 0.52 | 5.06 | 140 |
| Ryan Weathers | Marlins | 38.3 | 37 | 12 | 3.00 | 1.28 | 4.48 | 140 |
| Tylor Megill | Mets | 68.3 | 89 | 33 | 3.00 | 1.36 | 3.09 | 140 |
| Daysbel Hernández | Braves | 37.0 | 33 | 30 | 3.00 | 1.54 | 4.80 | 140 |
| Grant Holmes | Braves | 115.0 | 123 | 54 | 3.00 | 1.34 | 4.18 | 140 |
| Robert Gasser | Brewers | 5.7 | 5 | 4 | 3.00 | 1.59 | 5.75 | 140 |
| Mike Burrows | Pirates | 96.0 | 97 | 31 | 3.00 | 1.24 | 3.81 | 140 |
| Tyler Gilbert | White Sox | 51.0 | 49 | 24 | 3.00 | 1.25 | 3.86 | 140 |
| Will Vest | Tigers | 68.7 | 75 | 22 | 3.00 | 1.21 | 2.63 | 140 |
| Edward Cabrera | Marlins | 137.7 | 150 | 48 | 3.00 | 1.23 | 3.57 | 140 |
| Lake Bachar | Marlins | 71.0 | 75 | 30 | 3.00 | 1.20 | 4.09 | 140 |
| Dylan Lee | Braves | 68.3 | 76 | 14 | 3.00 | 0.98 | 3.96 | 140 |
| Tyler Holton | Tigers | 78.7 | 64 | 17 | 3.00 | 1.04 | 4.60 | 140 |
| Luke Williams | Braves | 6.0 | 4 | 1 | 3.00 | 1.17 | 4.43 | 140 |
| Carmen Mlodzinski | Pirates | 99.0 | 89 | 27 | 3.00 | 1.30 | 3.17 | 140 |
| Justin Sterner | Athletics | 65.0 | 70 | 21 | 3.00 | 1.05 | 3.92 | 140 |
| Chase Shugart | Pirates | 45.0 | 31 | 17 | 3.00 | 1.11 | 4.59 | 140 |
| Daniel Lynch IV | Royals | 67.7 | 45 | 26 | 3.00 | 1.36 | 4.46 | 140 |
| DL Hall | Brewers | 38.7 | 27 | 17 | 3.00 | 1.06 | 3.69 | 140 |
| Tobias Myers | Brewers | 50.7 | 38 | 15 | 3.00 | 1.36 | 3.77 | 140 |
| Drey Jameson | Diamondbacks | 3.0 | 0 | 3 | 3.00 | 2.33 | 6.10 | 140 |
| Elvis Alvarado | Athletics | 42.3 | 50 | 22 | 3.00 | 1.32 | 4.14 | 140 |
| Korey Lee | White Sox | 3.0 | 0 | 2 | 3.00 | 2.00 | 5.10 | 140 |
| Ryan Bergert | Royals | 76.3 | 73 | 35 | 3.00 | 1.26 | 3.93 | 140 |
| Jesús Luzardo | Phillies | 183.7 | 216 | 57 | 3.00 | 1.22 | 2.81 | 140 |
| Dauri Moreta | Pirates | 16.7 | 19 | 7 | 3.00 | 1.38 | 3.64 | 140 |
| Framber Valdez | Astros | 192.0 | 187 | 68 | 3.00 | 1.24 | 3.23 | 140 |
| Taylor Clarke | Royals | 55.3 | 44 | 9 | 3.00 | 0.85 | 3.88 | 140 |
| Camilo Doval | Yankees | 65.3 | 72 | 35 | 3.00 | 1.32 | 3.30 | 140 |
| Hogan Harris | Athletics | 64.7 | 65 | 33 | 3.00 | 1.35 | 3.63 | 140 |
| Nick Mears | Brewers | 56.7 | 46 | 13 | 3.00 | 0.97 | 3.77 | 140 |
| JT Brubaker | Yankees | 28.7 | 22 | 12 | 3.00 | 1.22 | 2.82 | 140 |
| Yerry De los Santos | Yankees | 35.7 | 28 | 17 | 3.00 | 1.51 | 3.32 | 140 |
| Kodai Senga | Mets | 113.3 | 109 | 55 | 3.00 | 1.31 | 4.01 | 140 |
| Max Kranick | Mets | 37.0 | 25 | 5 | 3.00 | 1.05 | 3.91 | 140 |
| Jordan Leasure | White Sox | 64.3 | 81 | 30 | 3.00 | 1.23 | 4.41 | 140 |
| Ty Adcock | Mets | 3.0 | 5 | 2 | 3.00 | 1.33 | 6.10 | 140 |
| Steven Cruz | Royals | 45.7 | 38 | 18 | 3.00 | 1.18 | 4.04 | 140 |
| Grant Anderson | Brewers | 69.7 | 74 | 29 | 3.00 | 1.26 | 3.72 | 140 |
| Quinn Priester | Brewers | 157.3 | 132 | 50 | 3.00 | 1.24 | 3.86 | 140 |
| Luis Gil | Yankees | 57.0 | 41 | 33 | 3.00 | 1.40 | 4.54 | 140 |
| Johan Oviedo | Pirates | 40.3 | 42 | 23 | 3.00 | 1.21 | 4.66 | 140 |
| Stephen Kolek | Royals | 112.7 | 77 | 31 | 3.00 | 1.14 | 3.60 | 140 |
| Tyler Owens | Tigers | 3.0 | 1 | 3 | 3.00 | 2.00 | 5.43 | 140 |
| Brenan Hanifee | Tigers | 60.0 | 40 | 14 | 3.00 | 1.32 | 3.12 | 140 |
| Casey Mize | Tigers | 149.0 | 139 | 36 | 3.00 | 1.27 | 3.79 | 140 |
| John Schreiber | Royals | 64.0 | 62 | 19 | 3.00 | 1.19 | 4.08 | 140 |
| Rico Garcia | Mets | 34.3 | 38 | 10 | 3.00 | 1.19 | 3.65 | 140 |
| Brent Headrick | Yankees | 23.0 | 30 | 7 | 3.00 | 1.04 | 3.67 | 140 |
| Brandon Waddell | Mets | 31.3 | 22 | 11 | 3.00 | 1.28 | 4.41 | 140 |
| Tim Hill | Yankees | 67.0 | 37 | 16 | 3.00 | 1.10 | 4.26 | 140 |
| Fernando Cruz | Yankees | 48.0 | 72 | 24 | 3.00 | 1.19 | 2.95 | 140 |
| Anthony Banda | Dodgers | 65.0 | 61 | 34 | 3.00 | 1.22 | 4.39 | 140 |
| Adrian Houser | White Sox | 125.0 | 92 | 38 | 3.00 | 1.28 | 3.58 | 140 |
| Tyler Glasnow | Dodgers | 90.3 | 106 | 43 | 3.00 | 1.10 | 3.62 | 140 |
| Kyle Finnegan | Nationals | 57.0 | 55 | 18 | 3.00 | 1.11 | 3.03 | 140 |
| Chad Patrick | Brewers | 119.7 | 127 | 40 | 3.00 | 1.28 | 3.39 | 140 |
| Dylan Dodd | Braves | 35.0 | 30 | 5 | 3.00 | 0.94 | 3.67 | 140 |
| Martín Pérez | White Sox | 56.0 | 44 | 22 | 3.00 | 1.11 | 4.10 | 140 |
| José Alvarado | Phillies | 26.0 | 32 | 7 | 3.00 | 1.31 | 3.45 | 140 |
| Pierce Johnson | Braves | 59.0 | 59 | 19 | 3.00 | 1.20 | 3.83 | 140 |
| Lou Trivino III | Dodgers | 47.7 | 37 | 18 | 3.00 | 1.34 | 4.32 | 140 |
| Steven Okert | Astros | 71.7 | 84 | 19 | 3.00 | 0.89 | 2.64 | 140 |
| Jake Bauers | Brewers | 5.0 | 1 | 3 | 3.00 | 2.20 | 4.50 | 140 |
| Hayden Harris | Braves | 2.7 | 0 | 2 | 3.00 | 1.88 | 5.35 | 140 |
| Brandon Woodruff | Brewers | 64.7 | 83 | 14 | 3.00 | 0.91 | 2.99 | 140 |
| Tyler Kinley | Braves | 72.7 | 73 | 33 | 3.00 | 1.18 | 3.53 | 140 |
| Michael Kelly | Athletics | 39.7 | 29 | 19 | 3.00 | 1.29 | 4.71 | 140 |
| Tim Mayza | Pirates | 16.7 | 15 | 5 | 3.00 | 1.32 | 3.76 | 140 |
| Clay Holmes | Mets | 165.7 | 129 | 66 | 3.00 | 1.30 | 3.84 | 140 |
| Carlos Rodón | Yankees | 195.3 | 203 | 73 | 3.00 | 1.05 | 3.61 | 140 |
| Raisel Iglesias | Braves | 67.3 | 73 | 16 | 3.00 | 1.00 | 3.19 | 140 |
| Huascar Brazobán | Mets | 63.0 | 57 | 27 | 3.00 | 1.24 | 3.81 | 140 |
| AJ Smith-Shawver | Braves | 44.3 | 42 | 21 | 3.00 | 1.42 | 3.80 | 140 |
| Randy Wynne | Reds | 3.0 | 3 | 1 | 3.00 | 1.33 | 6.43 | 140 |
| Orion Kerkering | Phillies | 60.0 | 65 | 27 | 3.00 | 1.37 | 3.58 | 140 |
| Luke Weaver | Yankees | 64.7 | 72 | 20 | 3.00 | 1.02 | 3.81 | 140 |
| Luis García | Nationals | 55.3 | 48 | 26 | 3.00 | 1.46 | 3.24 | 140 |
| Steven Wilson | White Sox | 55.3 | 51 | 22 | 3.00 | 1.30 | 4.09 | 140 |
| Michael Wacha | Royals | 172.7 | 126 | 45 | 3.00 | 1.22 | 3.55 | 140 |
| Clayton Kershaw | Dodgers | 112.7 | 84 | 35 | 3.00 | 1.22 | 3.46 | 140 |
| Tanner Banks | Phillies | 67.3 | 61 | 12 | 3.00 | 1.01 | 3.56 | 140 |
| Aaron Bummer | Braves | 54.3 | 51 | 17 | 3.00 | 1.25 | 2.88 | 140 |
| Jose Quintana | Brewers | 131.7 | 89 | 50 | 3.00 | 1.29 | 4.66 | 140 |
| Luis Morales | Athletics | 48.7 | 43 | 18 | 3.00 | 1.15 | 4.58 | 140 |
| Seranthony Domínguez | Blue Jays | 21.0 | 25 | 12 | 3.00 | 1.14 | 3.05 | 140 |
| Ranger Suarez | Phillies | 157.3 | 151 | 38 | 3.00 | 1.22 | 3.06 | 140 |
| Victor Vodnik | Rockies | 50.2 | 49 | 26 | 3.02 | 1.40 | 3.74 | 139 |
| Eric Orze | Rays | 41.2 | 40 | 19 | 3.02 | 1.37 | 3.80 | 139 |
| Brendon Little | Blue Jays | 68.1 | 91 | 45 | 3.03 | 1.36 | 2.79 | 139 |
| Gavin Williams | Guardians | 167.2 | 173 | 83 | 3.06 | 1.27 | 4.31 | 137 |
| Kyle Leahy | Cardinals | 88.0 | 80 | 28 | 3.07 | 1.23 | 2.98 | 137 |
| Yariel Rodríguez | Blue Jays | 73.0 | 66 | 34 | 3.08 | 1.15 | 4.11 | 136 |
| Chris Flexen | Cubs | 43.2 | 22 | 12 | 3.09 | 1.15 | 5.02 | 136 |
| Hunter Gaddis | Guardians | 66.2 | 73 | 21 | 3.11 | 1.19 | 3.42 | 135 |
| Chris Murphy | Red Sox | 34.2 | 30 | 20 | 3.12 | 1.18 | 4.62 | 135 |
| Wandy Peralta | Padres | 71.2 | 63 | 30 | 3.14 | 1.34 | 3.51 | 134 |
| Brennan Bernardino | Red Sox | 51.2 | 43 | 26 | 3.14 | 1.26 | 3.20 | 134 |
| Eric Lauer | Blue Jays | 104.2 | 102 | 26 | 3.18 | 1.11 | 3.76 | 132 |
| Matthew Boyd | Cubs | 179.2 | 154 | 42 | 3.21 | 1.09 | 3.46 | 131 |
| Trey Yesavage | Blue Jays | 14.0 | 16 | 7 | 3.21 | 1.43 | 2.31 | 131 |
| Joey Cantillo | Guardians | 95.1 | 108 | 42 | 3.21 | 1.26 | 3.52 | 131 |
| Colin Selby | Orioles | 14.0 | 14 | 2 | 3.21 | 1.29 | 3.39 | 131 |
| Logan Webb | Giants | 207.0 | 224 | 46 | 3.22 | 1.24 | 2.48 | 130 |
| Ben Lively | Guardians | 44.2 | 29 | 15 | 3.22 | 1.19 | 4.57 | 130 |
| Emmanuel Clase | Guardians | 47.1 | 47 | 12 | 3.23 | 1.23 | 2.42 | 130 |
| Hunter Strickland | Angels | 22.0 | 14 | 10 | 3.27 | 1.23 | 4.37 | 128 |
| Andrew Kittredge | Cubs | 21.2 | 32 | 3 | 3.32 | 0.83 | 2.35 | 127 |
| Nick Lodolo | Reds | 156.2 | 156 | 31 | 3.33 | 1.08 | 3.53 | 126 |
| Brayan Bello | Red Sox | 166.2 | 124 | 59 | 3.35 | 1.24 | 3.92 | 125 |
| Justin Wilson | Red Sox | 48.1 | 57 | 20 | 3.35 | 1.41 | 2.79 | 125 |
| Brock Burke | Angels | 61.2 | 52 | 18 | 3.36 | 1.23 | 3.98 | 125 |
| Luke Little | Cubs | 2.2 | 4 | 6 | 3.38 | 2.63 | 7.65 | 124 |
| Bryan Hoeing | Padres | 8.0 | 5 | 3 | 3.38 | 1.50 | 2.98 | 124 |
| Jaden Hill | Rockies | 29.1 | 31 | 12 | 3.38 | 1.33 | 3.10 | 124 |
| A.J. Puk | Diamondbacks | 8.0 | 12 | 2 | 3.38 | 1.25 | 4.10 | 124 |
| Ryne Nelson | Diamondbacks | 154.0 | 132 | 41 | 3.39 | 1.07 | 3.62 | 124 |
| Keegan Akin | Orioles | 63.1 | 59 | 33 | 3.41 | 1.37 | 4.86 | 123 |
| Lucas Giolito | Red Sox | 145.0 | 121 | 56 | 3.41 | 1.29 | 4.11 | 123 |
| Joe Ryan | Twins | 171.0 | 194 | 39 | 3.42 | 1.04 | 3.49 | 123 |
| Luis Mey | Reds | 21.0 | 21 | 17 | 3.43 | 1.62 | 5.39 | 122 |
| Michael King | Padres | 73.1 | 76 | 26 | 3.44 | 1.20 | 4.22 | 122 |
| Logan Gilbert | Mariners | 131.0 | 173 | 31 | 3.44 | 1.03 | 3.15 | 122 |
| Steven Matz | Cardinals | 55.0 | 47 | 9 | 3.44 | 1.18 | 2.83 | 122 |
| Jeremiah Estrada | Padres | 73.0 | 108 | 27 | 3.45 | 1.16 | 3.39 | 122 |
| Kody Funderburk | Twins | 41.0 | 40 | 18 | 3.51 | 1.51 | 3.10 | 120 |
| Phil Maton | Rangers | 23.0 | 33 | 8 | 3.52 | 0.96 | 2.40 | 119 |
| Luis Castillo | Mariners | 180.2 | 162 | 46 | 3.54 | 1.18 | 3.73 | 119 |
| Cooper Criswell | Red Sox | 17.2 | 9 | 5 | 3.57 | 1.58 | 5.19 | 118 |
| Shane Bieber | Blue Jays | 40.1 | 37 | 7 | 3.57 | 1.02 | 4.37 | 118 |
| Zack Littell | Rays | 133.1 | 89 | 21 | 3.58 | 1.12 | 4.78 | 117 |
| Kevin Gausman | Blue Jays | 193.0 | 189 | 50 | 3.59 | 1.06 | 3.33 | 117 |
| Ian Seymour | Rays | 57.0 | 64 | 19 | 3.63 | 1.18 | 2.99 | 116 |
| Javier Assad | Cubs | 37.0 | 23 | 12 | 3.65 | 1.22 | 3.88 | 115 |
| Robbie Ray | Giants | 182.1 | 186 | 73 | 3.65 | 1.21 | 3.83 | 115 |
| Jameson Taillon | Cubs | 129.2 | 98 | 27 | 3.68 | 1.06 | 4.62 | 114 |
| Nabil Crismatt | Diamondbacks | 34.0 | 25 | 9 | 3.71 | 1.44 | 4.72 | 113 |
| Shota Imanaga | Cubs | 144.2 | 117 | 26 | 3.73 | 0.99 | 4.81 | 113 |
| Joey Lucchesi | Giants | 38.1 | 31 | 12 | 3.76 | 1.23 | 3.78 | 112 |
| Jalen Beeks | Diamondbacks | 57.1 | 47 | 20 | 3.77 | 1.08 | 3.87 | 111 |
| Edwin Uceta | Rays | 76.0 | 103 | 27 | 3.79 | 1.17 | 3.34 | 111 |
| Landen Roupp | Giants | 106.2 | 102 | 45 | 3.80 | 1.48 | 3.80 | 111 |
| Mason Englert | Rays | 44.2 | 44 | 11 | 3.83 | 1.21 | 3.03 | 110 |
| Randy Vásquez | Padres | 133.2 | 78 | 52 | 3.84 | 1.32 | 4.66 | 109 |
| Hoby Milner | Rangers | 70.1 | 58 | 21 | 3.84 | 1.27 | 3.27 | 109 |
| Justin Verlander | Giants | 152.0 | 137 | 52 | 3.85 | 1.36 | 3.69 | 109 |
| Josh Winckowski | Red Sox | 11.2 | 9 | 5 | 3.86 | 1.37 | 2.83 | 109 |
| Dugan Darnell | Rockies | 11.2 | 5 | 7 | 3.86 | 1.46 | 5.24 | 109 |
| Jose Trevino | Reds | 2.1 | 1 | 1 | 3.86 | 2.14 | 3.58 | 109 |
| Ryan Pepiot | Rays | 167.2 | 167 | 61 | 3.86 | 1.16 | 4.22 | 109 |
| Marc Church | Rangers | 4.2 | 5 | 6 | 3.86 | 2.14 | 5.00 | 109 |
| Yimi García | Blue Jays | 21.0 | 25 | 12 | 3.86 | 1.19 | 3.67 | 109 |
| Jack Leiter | Rangers | 151.2 | 148 | 67 | 3.86 | 1.28 | 4.02 | 109 |
| Justin Topa | Twins | 60.0 | 49 | 18 | 3.90 | 1.43 | 2.80 | 108 |
| Ryan Thompson | Diamondbacks | 41.1 | 36 | 13 | 3.92 | 1.33 | 3.56 | 107 |
| John Curtiss | Diamondbacks | 36.2 | 24 | 5 | 3.93 | 0.93 | 3.98 | 107 |
| Colin Rea | Cubs | 159.1 | 127 | 44 | 3.95 | 1.25 | 3.97 | 106 |
| Juan Mejia | Rockies | 61.1 | 68 | 25 | 3.96 | 1.26 | 3.38 | 106 |
| Chris Bassitt | Blue Jays | 170.1 | 166 | 52 | 3.96 | 1.33 | 3.75 | 106 |
| Reid Detmers | Angels | 63.2 | 80 | 25 | 3.96 | 1.30 | 2.99 | 106 |
| Carlos Vargas | Mariners | 77.0 | 54 | 23 | 3.97 | 1.35 | 4.28 | 106 |
| Yuki Matsui | Padres | 63.1 | 61 | 33 | 3.98 | 1.36 | 4.80 | 106 |
| Graham Ashcraft | Reds | 65.1 | 64 | 25 | 3.99 | 1.42 | 2.69 | 105 |
| Yusei Kikuchi | Angels | 178.1 | 174 | 74 | 3.99 | 1.42 | 4.14 | 105 |
| David Robertson | Phillies | 17.7 | 22 | 8 | 4.00 | 1.47 | 4.91 | 105 |
| Roki Sasaki | Dodgers | 36.3 | 28 | 22 | 4.00 | 1.43 | 5.52 | 105 |
| Michael Lorenzen | Royals | 141.7 | 127 | 39 | 4.00 | 1.33 | 4.43 | 105 |
| Max Lazar | Phillies | 41.3 | 26 | 12 | 4.00 | 1.28 | 4.91 | 105 |
| José A. Ferrer | Nationals | 76.3 | 71 | 16 | 4.00 | 1.27 | 2.72 | 105 |
| Seth Lugo | Royals | 145.3 | 125 | 55 | 4.00 | 1.29 | 4.93 | 105 |
| Justin Wrobleski | Dodgers | 66.7 | 76 | 17 | 4.00 | 1.23 | 2.76 | 105 |
| Paul Gervase | Dodgers | 8.3 | 8 | 6 | 4.00 | 1.68 | 8.02 | 105 |
| Landon Knack | Dodgers | 42.3 | 42 | 19 | 4.00 | 1.39 | 5.53 | 105 |
| Cade Cavalli | Nationals | 48.7 | 40 | 15 | 4.00 | 1.48 | 4.25 | 105 |
| Brett de Geus | Phillies | 2.0 | 0 | 3 | 4.00 | 2.00 | 7.60 | 105 |
| MacKenzie Gore | Nationals | 159.7 | 185 | 64 | 4.00 | 1.35 | 3.61 | 105 |
| Brandon Eisert | White Sox | 69.7 | 74 | 25 | 4.00 | 1.44 | 4.29 | 105 |
| Jack Perkins | Athletics | 38.7 | 37 | 18 | 4.00 | 1.16 | 3.93 | 105 |
| Sean Burke | White Sox | 134.3 | 133 | 63 | 4.00 | 1.44 | 4.75 | 105 |
| Valente Bellozo | Marlins | 81.3 | 54 | 23 | 4.00 | 1.33 | 5.02 | 105 |
| Max Meyer | Marlins | 64.7 | 68 | 20 | 4.00 | 1.42 | 4.34 | 105 |
| Anthony Veneziano | Marlins | 25.0 | 25 | 11 | 4.00 | 1.56 | 4.50 | 105 |
| Dustin May | Dodgers | 132.3 | 123 | 56 | 4.00 | 1.42 | 4.57 | 105 |
| Spencer Strider | Braves | 125.3 | 131 | 51 | 4.00 | 1.40 | 4.30 | 105 |
| Jacob Misiorowski | Brewers | 66.0 | 87 | 31 | 4.00 | 1.24 | 3.45 | 105 |
| Tommy Kahnle | Tigers | 63.0 | 50 | 31 | 4.00 | 1.30 | 4.64 | 105 |
| Jacob Lopez | Athletics | 92.7 | 113 | 37 | 4.00 | 1.27 | 3.96 | 105 |
| Jackson Jobe | Tigers | 49.0 | 39 | 27 | 4.00 | 1.49 | 5.02 | 105 |
| Bubba Chandler | Pirates | 31.3 | 31 | 4 | 4.00 | 0.93 | 2.33 | 105 |
| Ronel Blanco | Astros | 48.3 | 48 | 20 | 4.00 | 1.18 | 4.24 | 105 |
| Jason Alexander | Athletics | 77.3 | 65 | 26 | 4.00 | 1.37 | 4.95 | 105 |
| Angel Zerpa | Royals | 64.7 | 58 | 22 | 4.00 | 1.38 | 3.73 | 105 |
| Dedniel Núñez | Mets | 9.7 | 11 | 6 | 4.00 | 1.24 | 4.03 | 105 |
| Keider Montero | Tigers | 90.7 | 72 | 31 | 4.00 | 1.39 | 4.83 | 105 |
| Kaleb Ort | Astros | 46.0 | 49 | 27 | 4.00 | 1.35 | 4.99 | 105 |
| Chase Lee | Tigers | 37.3 | 36 | 9 | 4.00 | 1.10 | 4.33 | 105 |
| Janson Junk | Marlins | 110.0 | 77 | 13 | 4.00 | 1.14 | 3.00 | 105 |
| Hayden Wesneski | Astros | 32.0 | 29 | 6 | 4.00 | 1.09 | 4.69 | 105 |
| Cole Henry | Nationals | 52.7 | 52 | 32 | 4.00 | 1.42 | 4.68 | 105 |
| Rafael Montero | Tigers | 60.3 | 58 | 37 | 4.00 | 1.31 | 4.09 | 105 |
| Tyler Matzek | Yankees | 6.3 | 7 | 5 | 4.00 | 2.53 | 3.26 | 105 |
| José Ureña | Mets | 55.0 | 34 | 23 | 4.00 | 1.45 | 5.01 | 105 |
| Adam Mazur | Marlins | 30.0 | 19 | 12 | 4.00 | 1.50 | 4.77 | 105 |
| Ben Casparius | Dodgers | 77.7 | 71 | 21 | 4.00 | 1.27 | 3.42 | 105 |
| Will Warren | Yankees | 162.3 | 171 | 65 | 4.00 | 1.37 | 3.96 | 105 |
| Jeffrey Springs | Athletics | 171.0 | 138 | 54 | 4.00 | 1.21 | 4.56 | 105 |
| Spencer Bivens | Giants | 81.0 | 61 | 25 | 4.00 | 1.33 | 3.48 | 105 |
| Brad Lord | Nationals | 130.7 | 108 | 43 | 4.00 | 1.29 | 4.13 | 105 |
| Taijuan Walker | Phillies | 123.7 | 86 | 42 | 4.00 | 1.41 | 4.94 | 105 |
| Daniel Robert | Phillies | 13.0 | 15 | 10 | 4.00 | 1.62 | 5.10 | 105 |
| Gregory Soto | Mets | 60.3 | 70 | 24 | 4.00 | 1.43 | 2.83 | 105 |
| Clayton Beeter | Nationals | 25.3 | 33 | 18 | 4.00 | 1.22 | 4.17 | 105 |
| Connor Seabold | Braves | 10.3 | 10 | 6 | 4.00 | 1.74 | 4.16 | 105 |
| Devin Williams | Yankees | 62.0 | 90 | 25 | 4.00 | 1.13 | 2.45 | 105 |
| Ben Bowden | Athletics | 10.7 | 7 | 5 | 4.00 | 1.31 | 5.63 | 105 |
| Jonathan Loáisiga | Yankees | 29.7 | 25 | 10 | 4.00 | 1.48 | 5.49 | 105 |
| Luke Jackson | Tigers | 51.0 | 38 | 28 | 4.00 | 1.35 | 4.28 | 105 |
| Cole Ragans | Royals | 61.7 | 98 | 20 | 4.00 | 1.18 | 2.37 | 105 |
| Tyler Alexander | Brewers | 97.7 | 82 | 30 | 4.00 | 1.40 | 3.54 | 105 |
| Tyler Ferguson | Athletics | 58.0 | 54 | 34 | 4.00 | 1.33 | 3.89 | 105 |
| Ryan Yarbrough | Yankees | 64.0 | 55 | 19 | 4.00 | 1.20 | 4.91 | 105 |
| Cristian Javier | Astros | 37.0 | 34 | 15 | 4.00 | 1.27 | 3.53 | 105 |
| Tanner Scott | Dodgers | 57.0 | 60 | 18 | 4.00 | 1.26 | 4.45 | 105 |
| Walker Buehler | Phillies | 126.0 | 92 | 61 | 4.00 | 1.52 | 5.36 | 105 |
| David Peterson | Mets | 168.7 | 150 | 65 | 4.00 | 1.37 | 3.33 | 105 |
| Danny Young | Mets | 8.3 | 13 | 3 | 4.00 | 1.44 | 1.06 | 105 |
| Ryan Helsley | Mets | 56.0 | 63 | 25 | 4.00 | 1.54 | 4.05 | 105 |
| Kyle Nicolas | Pirates | 38.0 | 34 | 18 | 4.00 | 1.37 | 3.76 | 105 |
| Ian Hamilton | Yankees | 40.0 | 42 | 22 | 4.00 | 1.25 | 4.28 | 105 |
| Michael Petersen | Marlins | 18.0 | 17 | 7 | 4.00 | 1.39 | 4.54 | 105 |
| Mitch Keller | Pirates | 176.3 | 150 | 51 | 4.00 | 1.26 | 3.81 | 105 |
| Enyel De Los Santos | Astros | 66.0 | 62 | 24 | 4.00 | 1.29 | 3.69 | 105 |
| Seth Johnson | Phillies | 12.7 | 17 | 4 | 4.00 | 1.18 | 4.44 | 105 |
| Eury Pérez | Marlins | 95.3 | 105 | 32 | 4.00 | 1.05 | 3.54 | 105 |
| Dietrich Enns | Tigers | 46.3 | 49 | 15 | 4.00 | 1.40 | 3.64 | 105 |
| Bryan Hudson | Brewers | 15.0 | 19 | 13 | 4.00 | 1.87 | 4.90 | 105 |
| Brandon Sproat | Mets | 20.7 | 17 | 7 | 4.00 | 1.21 | 2.47 | 105 |
| Michael Soroka | Nationals | 89.7 | 95 | 29 | 4.00 | 1.13 | 3.69 | 105 |
| Bailey Falter | Pirates | 125.3 | 81 | 46 | 4.00 | 1.28 | 4.88 | 105 |
| Aaron Civale | Brewers | 102.0 | 88 | 33 | 4.00 | 1.26 | 4.38 | 105 |
| Paul Sewald | Tigers | 19.7 | 20 | 6 | 4.00 | 1.22 | 4.63 | 105 |
| Sauryn Lao | Nationals | 11.0 | 9 | 2 | 4.00 | 1.45 | 4.37 | 105 |
| Mark Leiter Jr. | Yankees | 48.3 | 54 | 17 | 4.00 | 1.53 | 3.27 | 105 |
| Konnor Pilkington | Nationals | 28.3 | 34 | 17 | 4.00 | 1.38 | 5.71 | 105 |
| Grant Taylor | White Sox | 36.7 | 54 | 15 | 4.00 | 1.42 | 1.38 | 105 |
| Fraser Ellard | White Sox | 17.0 | 22 | 19 | 4.00 | 1.59 | 4.63 | 105 |
| Ryan Borucki | Pirates | 35.0 | 32 | 16 | 4.00 | 1.29 | 4.13 | 105 |
| Davis Martin | White Sox | 142.7 | 104 | 48 | 4.00 | 1.29 | 4.47 | 105 |
| Justin Hagenman | Mets | 23.7 | 23 | 2 | 4.00 | 1.10 | 3.61 | 105 |
| Luis Severino | Athletics | 162.7 | 124 | 50 | 4.00 | 1.30 | 3.78 | 105 |
| Jack Flaherty | Tigers | 161.0 | 188 | 59 | 4.00 | 1.28 | 3.72 | 105 |
| Brady Singer | Reds | 169.2 | 163 | 60 | 4.03 | 1.24 | 3.70 | 104 |
| Simeon Woods Richardson | Twins | 111.1 | 107 | 46 | 4.04 | 1.28 | 4.41 | 104 |
| Tommy Henry | Diamondbacks | 6.2 | 8 | 1 | 4.05 | 1.05 | 7.29 | 104 |
| José De León | Red Sox | 6.2 | 8 | 3 | 4.05 | 1.65 | 4.07 | 104 |
| Juan Burgos | Mariners | 6.2 | 8 | 2 | 4.05 | 1.35 | 1.49 | 104 |
| Justin Martinez | Diamondbacks | 15.1 | 22 | 12 | 4.11 | 1.24 | 3.43 | 102 |
| Ryan Walker | Giants | 61.1 | 60 | 18 | 4.11 | 1.27 | 2.87 | 102 |
| Matt Festa | Guardians | 54.2 | 56 | 15 | 4.12 | 1.08 | 2.82 | 102 |
| Hunter Dobbins | Red Sox | 61.0 | 45 | 17 | 4.13 | 1.28 | 3.74 | 102 |
| Luis Guerrero | Red Sox | 17.1 | 10 | 14 | 4.15 | 1.33 | 4.39 | 101 |
| José Berríos | Blue Jays | 166.0 | 138 | 56 | 4.17 | 1.30 | 4.49 | 101 |
| Juan Morillo | Diamondbacks | 34.1 | 36 | 20 | 4.19 | 1.69 | 3.51 | 100 |
| Dean Kremer | Orioles | 171.2 | 142 | 45 | 4.19 | 1.21 | 3.90 | 100 |
| Matthew Liberatore | Cardinals | 151.2 | 122 | 40 | 4.21 | 1.31 | 3.91 | 100 |
| George Kirby | Mariners | 126.0 | 137 | 29 | 4.21 | 1.19 | 3.16 | 100 |
| Scott Barlow | Reds | 68.1 | 75 | 45 | 4.21 | 1.39 | 4.41 | 100 |
| Merrill Kelly | Rangers | 55.1 | 46 | 10 | 4.23 | 1.25 | 4.10 | 99 |
| Tanner Bibee | Guardians | 182.1 | 162 | 54 | 4.24 | 1.23 | 4.14 | 99 |
| Justin Slaten | Red Sox | 34.0 | 25 | 10 | 4.24 | 1.09 | 3.66 | 99 |
| Jackson Kowar | Mariners | 17.0 | 15 | 7 | 4.24 | 1.24 | 5.63 | 99 |
| Logan Allen | Guardians | 156.2 | 122 | 62 | 4.25 | 1.40 | 4.23 | 99 |
| Dillon Tate | Blue Jays | 6.1 | 8 | 6 | 4.26 | 2.21 | 5.56 | 99 |
| José Soriano | Angels | 169.0 | 152 | 78 | 4.26 | 1.40 | 3.61 | 99 |
| Sonny Gray | Cardinals | 180.2 | 201 | 38 | 4.28 | 1.23 | 3.31 | 98 |
| Slade Cecconi | Guardians | 132.0 | 109 | 32 | 4.30 | 1.19 | 4.54 | 98 |
| Logan Evans | Mariners | 81.1 | 59 | 31 | 4.32 | 1.39 | 4.88 | 97 |
| Ryan Pressly | Cubs | 41.1 | 28 | 17 | 4.35 | 1.52 | 4.88 | 97 |
| Luis Ortiz | Guardians | 88.2 | 96 | 42 | 4.36 | 1.38 | 4.12 | 96 |
| Jeff Hoffman | Blue Jays | 68.0 | 84 | 27 | 4.37 | 1.19 | 4.69 | 96 |
| Paxton Schultz | Blue Jays | 24.2 | 28 | 8 | 4.38 | 1.42 | 3.93 | 96 |
| Patrick Corbin | Rangers | 155.1 | 131 | 51 | 4.40 | 1.36 | 4.16 | 95 |
| Taylor Rashi | Diamondbacks | 16.1 | 22 | 8 | 4.41 | 1.47 | 1.86 | 95 |
| Michael McGreevy | Cardinals | 95.2 | 58 | 20 | 4.42 | 1.25 | 4.15 | 95 |
| Mason Fluharty | Blue Jays | 52.2 | 56 | 24 | 4.44 | 1.14 | 3.83 | 95 |
| Nick Martinez | Reds | 165.2 | 116 | 42 | 4.45 | 1.21 | 4.19 | 94 |
| José Fermin | Angels | 34.1 | 39 | 23 | 4.46 | 1.40 | 5.89 | 94 |
| Jose Herrera | Diamondbacks | 2.0 | 0 | 0 | 4.50 | 2.00 | 3.10 | 93 |
| Brandyn Garcia | Mariners | 2.0 | 1 | 3 | 4.50 | 3.50 | 6.60 | 93 |
| Cole Sands | Twins | 72.0 | 64 | 19 | 4.50 | 1.17 | 3.38 | 93 |
| Keaton Winn | Giants | 10.0 | 9 | 2 | 4.50 | 1.40 | 3.20 | 93 |
| Zach Maxwell | Reds | 10.0 | 13 | 4 | 4.50 | 1.40 | 5.60 | 93 |
| Griffin Jax | Twins | 46.0 | 72 | 13 | 4.50 | 1.28 | 1.95 | 93 |
| Ryan Brasier | Cubs | 26.0 | 20 | 5 | 4.50 | 1.23 | 3.14 | 93 |
| Jacob Stallings | Rockies | 2.0 | 1 | 0 | 4.50 | 1.00 | 2.10 | 93 |
| Brent Suter | Reds | 67.2 | 53 | 18 | 4.52 | 1.29 | 4.45 | 93 |
| Lyon Richardson | Reds | 37.2 | 30 | 21 | 4.54 | 1.54 | 3.88 | 93 |
| Dylan Cease | Padres | 168.0 | 215 | 71 | 4.55 | 1.33 | 3.43 | 92 |
| Kyle Harrison | Giants | 23.2 | 25 | 9 | 4.56 | 1.27 | 4.35 | 92 |
| Tyler Anderson | Angels | 136.1 | 104 | 57 | 4.56 | 1.41 | 5.50 | 92 |
| Chase Burns | Reds | 43.1 | 67 | 16 | 4.57 | 1.32 | 2.61 | 92 |
| Zak Kent | Guardians | 17.2 | 16 | 8 | 4.58 | 1.42 | 3.39 | 92 |
| Yaramil Hiraldo | Orioles | 19.2 | 21 | 9 | 4.58 | 1.32 | 5.03 | 92 |
| Zack Kelly | Red Sox | 35.1 | 35 | 12 | 4.58 | 1.33 | 3.24 | 92 |
| Tristan Beck | Giants | 56.2 | 41 | 16 | 4.61 | 1.11 | 4.11 | 91 |
| Kyle Backhus | Diamondbacks | 25.1 | 22 | 8 | 4.62 | 1.42 | 3.86 | 91 |
| Ian Gibaut | Reds | 25.1 | 15 | 8 | 4.62 | 1.34 | 4.41 | 91 |
| Tomoyuki Sugano | Orioles | 157.0 | 106 | 36 | 4.64 | 1.33 | 5.17 | 91 |
| John King | Cardinals | 48.1 | 28 | 14 | 4.66 | 1.63 | 4.97 | 90 |
| Joe Boyle | Rays | 52.0 | 58 | 28 | 4.67 | 1.37 | 3.98 | 90 |
| Trent Thornton | Mariners | 42.1 | 32 | 14 | 4.68 | 1.30 | 4.43 | 90 |
| Andre Granillo | Cardinals | 21.0 | 18 | 7 | 4.71 | 1.38 | 4.24 | 89 |
| Ryan Zeferjahn | Angels | 57.0 | 73 | 35 | 4.74 | 1.47 | 5.12 | 89 |
| Ryan Feltner | Rockies | 30.1 | 25 | 12 | 4.75 | 1.48 | 4.36 | 88 |
| Carson Seymour | Giants | 36.0 | 26 | 13 | 4.75 | 1.39 | 5.99 | 88 |
| Bryan Baker | Rays | 30.1 | 34 | 8 | 4.75 | 1.12 | 3.80 | 88 |
| Justin Steele | Cubs | 22.2 | 21 | 5 | 4.76 | 1.15 | 4.81 | 88 |
| Kyle Hendricks | Angels | 164.2 | 114 | 43 | 4.76 | 1.28 | 4.48 | 88 |
| Hayden Birdsong | Giants | 65.2 | 68 | 37 | 4.80 | 1.49 | 4.71 | 88 |
| Gavin Hollowell | Cubs | 9.1 | 10 | 7 | 4.82 | 1.71 | 4.64 | 87 |
| Zac Gallen | Diamondbacks | 192.0 | 175 | 66 | 4.83 | 1.26 | 4.41 | 87 |
| Miles Mikolas | Cardinals | 156.1 | 100 | 37 | 4.84 | 1.32 | 4.94 | 87 |
| Tim Herrin | Guardians | 42.2 | 45 | 30 | 4.85 | 1.57 | 4.64 | 87 |
| Shane Baz | Rays | 166.1 | 176 | 64 | 4.87 | 1.33 | 4.17 | 86 |
| Michael Tonkin | Twins | 24.0 | 19 | 8 | 4.88 | 1.17 | 4.14 | 86 |
| Emerson Hancock | Mariners | 90.0 | 64 | 31 | 4.90 | 1.38 | 4.88 | 86 |
| Omar Cruz | Padres | 3.2 | 5 | 3 | 4.91 | 1.91 | 2.79 | 86 |
| Philip Abner | Diamondbacks | 3.2 | 5 | 3 | 4.91 | 2.18 | 2.79 | 86 |
| Jake Eder | Angels | 18.1 | 15 | 9 | 4.91 | 1.31 | 5.09 | 86 |
| Kyle Freeland | Rockies | 162.2 | 124 | 38 | 4.98 | 1.42 | 4.04 | 84 |
| Seth Halvorsen | Rockies | 39.2 | 36 | 21 | 4.99 | 1.56 | 5.19 | 84 |
| Jake Bird | Yankees | 55.3 | 66 | 25 | 5.00 | 1.54 | 3.71 | 84 |
| Joe Ross | Phillies | 51.0 | 39 | 18 | 5.00 | 1.47 | 4.67 | 84 |
| Mitchell Parker | Nationals | 164.7 | 103 | 58 | 5.00 | 1.43 | 4.88 | 84 |
| Shawn Dubin | Astros | 33.7 | 28 | 11 | 5.00 | 1.43 | 4.73 | 84 |
| Julian Fernández | Nationals | 5.0 | 5 | 2 | 5.00 | 1.00 | 7.50 | 84 |
| Charlie Morton | Tigers | 142.0 | 149 | 72 | 5.00 | 1.58 | 4.63 | 84 |
| Rich Hill | Royals | 9.0 | 4 | 8 | 5.00 | 1.89 | 7.77 | 84 |
| Grant Holman | Athletics | 23.0 | 17 | 9 | 5.00 | 1.52 | 4.49 | 84 |
| JP Sears | Athletics | 135.7 | 117 | 36 | 5.00 | 1.32 | 5.05 | 84 |
| J.T. Ginn | Athletics | 90.3 | 99 | 31 | 5.00 | 1.36 | 4.38 | 84 |
| Justin Garza | Mets | 6.7 | 3 | 1 | 5.00 | 1.35 | 4.60 | 84 |
| Easton McGee | Brewers | 14.7 | 13 | 5 | 5.00 | 1.36 | 3.24 | 84 |
| Jonathan Cannon | White Sox | 103.7 | 86 | 38 | 5.00 | 1.49 | 4.92 | 84 |
| Erick Fedde | Brewers | 141.0 | 83 | 67 | 5.00 | 1.52 | 5.10 | 84 |
| Joey Wentz | Pirates | 98.0 | 92 | 43 | 5.00 | 1.56 | 4.00 | 84 |
| Sandy Alcantara | Marlins | 174.7 | 142 | 57 | 5.00 | 1.27 | 4.09 | 84 |
| Bryce Elder | Braves | 156.3 | 131 | 51 | 5.00 | 1.39 | 4.40 | 84 |
| Kirby Yates | Dodgers | 41.3 | 52 | 17 | 5.00 | 1.33 | 4.65 | 84 |
| Spencer Arrighetti | Astros | 35.3 | 31 | 20 | 5.00 | 1.42 | 5.25 | 84 |
| Reynaldo López | Braves | 5.0 | 1 | 2 | 5.00 | 2.20 | 6.50 | 84 |
| Richard Fitts | Red Sox | 45.0 | 40 | 16 | 5.00 | 1.31 | 5.57 | 84 |
| Scott Blewett | Braves | 44.3 | 35 | 18 | 5.00 | 1.42 | 5.38 | 84 |
| Hunter Stratton | Pirates | 19.0 | 16 | 7 | 5.00 | 1.58 | 4.57 | 84 |
| Yoendrys Gómez | Dodgers | 62.7 | 58 | 27 | 5.00 | 1.39 | 5.03 | 84 |
| Logan VanWey | Astros | 10.7 | 7 | 3 | 5.00 | 1.69 | 5.07 | 84 |
| Matt Krook | Athletics | 3.3 | 3 | 1 | 5.00 | 1.80 | 2.20 | 84 |
| Yohan Ramírez | Pirates | 33.3 | 45 | 16 | 5.00 | 1.47 | 3.40 | 84 |
| Seth Martinez | Marlins | 6.7 | 4 | 3 | 5.00 | 1.05 | 7.15 | 84 |
| Caleb Freeman | White Sox | 3.3 | 3 | 1 | 5.00 | 1.80 | 6.10 | 84 |
| Codi Heuer | Tigers | 4.7 | 5 | 2 | 5.00 | 1.29 | 10.59 | 84 |
| Sean Manaea | Mets | 60.7 | 75 | 12 | 5.00 | 1.22 | 4.01 | 84 |
| Cam Booser | White Sox | 31.0 | 35 | 19 | 5.00 | 1.52 | 6.04 | 84 |
| Angel Perdomo | Athletics | 3.3 | 2 | 3 | 5.00 | 1.50 | 4.60 | 84 |
| Ryan Gusto | Astros | 101.7 | 97 | 36 | 5.00 | 1.48 | 4.43 | 84 |
| Sean Guenther | Tigers | 10.3 | 8 | 5 | 5.00 | 1.45 | 3.00 | 84 |
| Osvaldo Bido | Athletics | 79.7 | 68 | 35 | 5.00 | 1.61 | 5.81 | 84 |
| Ryne Stanek | Mets | 56.0 | 58 | 32 | 5.00 | 1.57 | 4.37 | 84 |
| Blake Treinen | Dodgers | 26.7 | 36 | 19 | 5.00 | 1.84 | 4.49 | 84 |
| Nick Hernandez | Astros | 10.7 | 11 | 8 | 5.00 | 1.88 | 6.94 | 84 |
| Chris Paddack | Tigers | 158.0 | 112 | 37 | 5.00 | 1.28 | 4.94 | 84 |
| Jake Irvin | Nationals | 180.0 | 124 | 62 | 5.00 | 1.43 | 5.50 | 84 |
| Colton Gordon | Astros | 86.0 | 72 | 19 | 5.00 | 1.42 | 5.26 | 84 |
| Jackson Rutledge | Nationals | 73.3 | 65 | 24 | 5.00 | 1.51 | 5.15 | 84 |
| Tony Gonsolin | Dodgers | 36.0 | 38 | 18 | 5.00 | 1.42 | 5.74 | 84 |
| Sam Long | Royals | 40.3 | 33 | 22 | 5.00 | 1.74 | 5.36 | 84 |
| Andrew Heaney | Pirates | 122.3 | 86 | 40 | 5.00 | 1.38 | 5.33 | 84 |
| Davis Daniel | Braves | 10.0 | 9 | 7 | 5.00 | 1.60 | 4.70 | 84 |
| Thomas Hatch | Royals | 34.0 | 22 | 17 | 5.00 | 1.68 | 5.98 | 84 |
| Jesus Tinoco | Marlins | 19.3 | 10 | 8 | 5.00 | 1.29 | 3.98 | 84 |
| Mitch Spence | Athletics | 84.7 | 66 | 26 | 5.00 | 1.44 | 4.92 | 84 |
| Carson Whisenhunt | Giants | 23.1 | 16 | 12 | 5.01 | 1.46 | 6.65 | 84 |
| Eduardo Rodriguez | Diamondbacks | 154.1 | 143 | 60 | 5.02 | 1.54 | 4.52 | 84 |
| Pierson Ohl | Twins | 30.0 | 27 | 7 | 5.10 | 1.50 | 4.17 | 82 |
| Bailey Ober | Twins | 146.1 | 120 | 31 | 5.10 | 1.30 | 4.76 | 82 |
| Yennier Cano | Orioles | 58.0 | 53 | 24 | 5.12 | 1.48 | 4.08 | 82 |
| Anthony DeSclafani | Diamondbacks | 38.2 | 36 | 12 | 5.12 | 1.27 | 5.90 | 82 |
| Alek Jacob | Padres | 33.1 | 23 | 14 | 5.13 | 1.50 | 5.34 | 82 |
| Gregory Santos | Mariners | 7.0 | 0 | 8 | 5.14 | 2.29 | 6.53 | 82 |
| Max Scherzer | Blue Jays | 85.0 | 82 | 23 | 5.19 | 1.29 | 4.89 | 81 |
| Cade Povich | Orioles | 112.1 | 118 | 43 | 5.21 | 1.50 | 4.12 | 81 |
| Brandon Pfaadt | Diamondbacks | 176.2 | 147 | 37 | 5.25 | 1.33 | 3.98 | 80 |
| Justin Bruihl | Blue Jays | 13.2 | 18 | 7 | 5.27 | 1.90 | 3.93 | 80 |
| Andre Pallante | Cardinals | 162.2 | 111 | 62 | 5.31 | 1.44 | 4.56 | 79 |
| Sean Reynolds | Padres | 27.0 | 25 | 17 | 5.33 | 1.37 | 5.06 | 79 |
| Yu Darvish | Padres | 72.0 | 68 | 19 | 5.38 | 1.18 | 4.53 | 78 |
| Jesse Hahn | Mariners | 5.0 | 3 | 5 | 5.40 | 2.20 | 7.50 | 78 |
| Grant Wolfram | Orioles | 26.2 | 31 | 15 | 5.40 | 1.88 | 3.44 | 78 |
| David Festa | Twins | 53.1 | 53 | 19 | 5.40 | 1.28 | 4.63 | 78 |
| Jesse Scholtens | Rays | 8.1 | 12 | 3 | 5.40 | 1.44 | 2.85 | 78 |
| Brian Van Belle | Rays | 8.1 | 6 | 0 | 5.40 | 1.56 | 4.83 | 78 |
| Collin Snider | Mariners | 26.1 | 24 | 6 | 5.47 | 1.44 | 3.44 | 77 |
| Connor Brogdon | Angels | 47.0 | 49 | 18 | 5.55 | 1.34 | 5.21 | 76 |
| Zebby Matthews | Twins | 79.1 | 88 | 24 | 5.56 | 1.49 | 3.76 | 76 |
| Chad Green | Blue Jays | 43.2 | 35 | 13 | 5.56 | 1.47 | 6.60 | 76 |
| Casey Legumina | Mariners | 49.2 | 55 | 25 | 5.62 | 1.45 | 4.24 | 75 |
| Mason Montgomery | Rays | 46.0 | 63 | 27 | 5.67 | 1.65 | 3.82 | 74 |
| Luis Curvelo | Rangers | 19.0 | 20 | 10 | 5.68 | 1.42 | 4.63 | 74 |
| Bryce Miller | Mariners | 90.1 | 74 | 34 | 5.68 | 1.41 | 5.04 | 74 |
| Bryce Jarvis | Diamondbacks | 22.0 | 21 | 10 | 5.73 | 1.50 | 4.33 | 73 |
| Kumar Rocker | Rangers | 64.1 | 56 | 23 | 5.74 | 1.46 | 4.66 | 73 |
| Julian Merryweather | Cubs | 18.2 | 15 | 11 | 5.79 | 1.82 | 4.69 | 73 |
| Carson Fulmer | Angels | 29.1 | 26 | 11 | 5.83 | 1.23 | 4.68 | 72 |
| Kyle Hart | Padres | 43.0 | 37 | 13 | 5.86 | 1.19 | 5.01 | 72 |
| Kevin Kelly | Rays | 39.2 | 35 | 9 | 5.90 | 1.36 | 5.65 | 71 |
| Garrett McDaniels | Angels | 10.2 | 6 | 8 | 5.91 | 1.97 | 6.83 | 71 |
| Ben Brown | Cubs | 106.1 | 121 | 32 | 5.92 | 1.44 | 3.93 | 71 |
| Zach Eflin | Orioles | 71.1 | 50 | 13 | 5.93 | 1.42 | 5.53 | 71 |
| Vinny Capra | Brewers | 3.0 | 1 | 0 | 6.00 | 1.67 | 6.77 | 70 |
| Andrew Hoffmann | Royals | 12.0 | 12 | 10 | 6.00 | 2.00 | 5.77 | 70 |
| Mason Barnett | Athletics | 22.3 | 18 | 11 | 6.00 | 1.66 | 4.71 | 70 |
| Carlos Rodriguez | Brewers | 9.7 | 11 | 9 | 6.00 | 2.28 | 4.96 | 70 |
| Mick Abel | Phillies | 39.0 | 39 | 16 | 6.00 | 1.51 | 5.00 | 70 |
| Ethan Roberts | Cubs | 9.0 | 6 | 2 | 6.00 | 1.33 | 6.77 | 70 |
| Beau Brieske | Tigers | 22.0 | 16 | 12 | 6.00 | 1.64 | 6.24 | 70 |
| Shinnosuke Ogasawara | Nationals | 38.7 | 30 | 17 | 6.00 | 1.55 | 5.89 | 70 |
| Héctor Neris | Astros | 26.7 | 35 | 16 | 6.00 | 1.69 | 5.20 | 70 |
| Joel Payamps | Brewers | 26.3 | 24 | 9 | 6.00 | 1.52 | 4.28 | 70 |
| Bryse Wilson | White Sox | 47.3 | 28 | 19 | 6.00 | 1.82 | 6.14 | 70 |
| Génesis Cabrera | Pirates | 42.7 | 35 | 18 | 6.00 | 1.50 | 6.38 | 70 |
| Lance McCullers Jr. | Astros | 55.3 | 61 | 39 | 6.00 | 1.81 | 5.36 | 70 |
| Elvis Peguero | Brewers | 9.3 | 8 | 6 | 6.00 | 1.93 | 4.71 | 70 |
| Trevor Williams | Nationals | 82.7 | 65 | 21 | 6.00 | 1.54 | 4.02 | 70 |
| Corbin Martin | Orioles | 18.0 | 23 | 9 | 6.00 | 1.72 | 4.93 | 70 |
| Frankie Montas | Mets | 38.7 | 32 | 14 | 6.00 | 1.60 | 5.22 | 70 |
| Cal Quantrill | Marlins | 117.7 | 85 | 35 | 6.00 | 1.45 | 4.98 | 70 |
| Xzavion Curry | Marlins | 3.0 | 1 | 3 | 6.00 | 2.33 | 5.43 | 70 |
| Carlos Hernández | Tigers | 43.3 | 39 | 22 | 6.00 | 1.66 | 4.02 | 70 |
| Paul Blackburn | Mets | 39.0 | 34 | 12 | 6.00 | 1.51 | 4.28 | 70 |
| Austin Hedges | Guardians | 3.0 | 1 | 1 | 6.00 | 2.33 | 3.43 | 70 |
| Marcus Stroman | Yankees | 39.0 | 26 | 16 | 6.00 | 1.54 | 5.00 | 70 |
| Chas McCormick | Astros | 3.0 | 1 | 2 | 6.00 | 1.67 | 4.43 | 70 |
| Dane Dunning | Braves | 20.7 | 21 | 7 | 6.00 | 1.50 | 4.60 | 70 |
| Jack Little | Dodgers | 3.0 | 2 | 1 | 6.00 | 1.67 | 2.77 | 70 |
| John Rooney | Astros | 1.3 | 2 | 1 | 6.00 | 1.50 | 12.12 | 70 |
| Matt Sauer | Dodgers | 29.7 | 24 | 8 | 6.00 | 1.45 | 4.92 | 70 |
| Scott McGough | Athletics | 16.0 | 16 | 7 | 6.00 | 1.56 | 5.66 | 70 |
| Luis Contreras | Astros | 12.0 | 13 | 8 | 6.00 | 1.58 | 5.10 | 70 |
| José Leclerc | Athletics | 9.0 | 8 | 5 | 6.00 | 2.00 | 7.32 | 70 |
| T.J. McFarland | Athletics | 15.7 | 7 | 3 | 6.00 | 1.85 | 4.44 | 70 |
| Jorge López | Nationals | 24.7 | 17 | 7 | 6.00 | 1.30 | 3.10 | 70 |
| Nestor Cortes | Brewers | 34.3 | 29 | 20 | 6.00 | 1.63 | 8.08 | 70 |
| Aaron Nola | Phillies | 94.3 | 97 | 28 | 6.00 | 1.35 | 4.41 | 70 |
| Gunnar Hoglund | Athletics | 32.3 | 23 | 11 | 6.00 | 1.52 | 6.72 | 70 |
| Caleb Boushley | Rangers | 43.1 | 41 | 14 | 6.02 | 1.57 | 3.68 | 70 |
| Bowden Francis | Blue Jays | 64.0 | 54 | 27 | 6.05 | 1.53 | 6.54 | 69 |
| Payton Tolle | Red Sox | 16.1 | 19 | 8 | 6.06 | 1.59 | 6.27 | 69 |
| Carson Spiers | Reds | 13.1 | 11 | 7 | 6.08 | 1.50 | 6.00 | 69 |
| Yosver Zulueta | Reds | 7.1 | 5 | 4 | 6.14 | 1.23 | 5.21 | 68 |
| Nick Anderson | Rockies | 14.2 | 10 | 2 | 6.14 | 1.30 | 4.86 | 68 |
| Matt Bowman | Orioles | 24.2 | 18 | 6 | 6.20 | 1.50 | 4.50 | 68 |
| Sam Bachman | Angels | 20.1 | 18 | 10 | 6.20 | 1.57 | 3.45 | 68 |
| Ben Joyce | Angels | 4.1 | 1 | 1 | 6.23 | 1.38 | 6.51 | 67 |
| Brandon Young | Orioles | 57.2 | 47 | 22 | 6.24 | 1.54 | 5.34 | 67 |
| Porter Hodge | Cubs | 33.0 | 40 | 18 | 6.27 | 1.58 | 5.86 | 67 |
| Jordan Wicks | Cubs | 14.1 | 13 | 1 | 6.28 | 1.74 | 3.31 | 67 |
| Gordon Graceffo | Cardinals | 43.0 | 40 | 13 | 6.28 | 1.47 | 2.75 | 67 |
| Tanner Gordon | Rockies | 75.1 | 62 | 17 | 6.33 | 1.50 | 4.90 | 66 |
| Kai-Wei Teng | Giants | 29.2 | 39 | 17 | 6.37 | 1.55 | 3.07 | 66 |
| Sam Moll | Reds | 18.1 | 22 | 10 | 6.38 | 1.42 | 5.20 | 66 |
| Caden Dana | Angels | 32.1 | 33 | 18 | 6.40 | 1.48 | 6.37 | 66 |
| Jake Woodford | Diamondbacks | 36.1 | 23 | 13 | 6.44 | 1.60 | 3.99 | 65 |
| Jordan Hicks | Giants | 48.2 | 43 | 20 | 6.47 | 1.54 | 3.37 | 65 |
| Chase Dollander | Rockies | 98.0 | 82 | 49 | 6.52 | 1.55 | 5.31 | 64 |
| Liam Hendriks | Red Sox | 13.2 | 12 | 7 | 6.59 | 1.39 | 4.84 | 64 |
| Zach Agnos | Rockies | 31.1 | 19 | 17 | 6.61 | 1.53 | 5.61 | 64 |
| Taj Bradley | Twins | 31.1 | 32 | 12 | 6.61 | 1.40 | 4.71 | 64 |
| Antonio Senzatela | Rockies | 130.0 | 73 | 47 | 6.65 | 1.84 | 5.26 | 63 |
| Mitch Farris | Angels | 24.1 | 24 | 11 | 6.66 | 1.44 | 4.64 | 63 |
| Easton Lucas | Blue Jays | 24.1 | 23 | 12 | 6.66 | 1.52 | 5.38 | 63 |
| Germán Márquez | Rockies | 126.1 | 83 | 48 | 6.70 | 1.71 | 5.30 | 63 |
| Kevin Newman | Angels | 4.0 | 0 | 0 | 6.75 | 1.00 | 9.60 | 62 |
| Wade Miley | Reds | 12.0 | 7 | 6 | 6.75 | 1.75 | 6.68 | 62 |
| Mason Black | Giants | 4.0 | 5 | 0 | 6.75 | 1.25 | 7.10 | 62 |
| Jovani Morán | Red Sox | 4.0 | 5 | 3 | 6.75 | 2.00 | 2.85 | 62 |
| Scott Alexander | Giants | 1.1 | 2 | 2 | 6.75 | 3.75 | 16.74 | 62 |
| Jack Kochanowicz | Angels | 111.0 | 72 | 58 | 6.81 | 1.75 | 5.83 | 62 |
| Mike Clevinger | White Sox | 5.7 | 3 | 8 | 7.00 | 2.29 | 6.27 | 60 |
| Sawyer Gipson-Long | Tigers | 31.3 | 26 | 6 | 7.00 | 1.28 | 5.33 | 60 |
| Tayler Scott | Astros | 27.3 | 24 | 18 | 7.00 | 1.90 | 6.17 | 60 |
| José Urquidy | Tigers | 2.3 | 3 | 3 | 7.00 | 3.00 | 4.39 | 60 |
| Jonah Tong | Mets | 18.7 | 22 | 9 | 7.00 | 1.77 | 4.28 | 60 |
| John Brebbia | Tigers | 23.3 | 26 | 12 | 7.00 | 1.71 | 5.20 | 60 |
| Josh Simpson | Marlins | 30.7 | 36 | 22 | 7.00 | 1.83 | 5.02 | 60 |
| Craig Yoho | Brewers | 8.7 | 7 | 9 | 7.00 | 1.96 | 6.10 | 60 |
| Penn Murfee | White Sox | 12.7 | 13 | 5 | 7.00 | 1.89 | 5.31 | 60 |
| Colin Holderman | Pirates | 25.7 | 18 | 16 | 7.00 | 1.95 | 5.59 | 60 |
| Bruce Zimmermann | Brewers | 6.0 | 1 | 2 | 7.00 | 1.50 | 8.10 | 60 |
| Kenta Maeda | Tigers | 8.0 | 8 | 6 | 7.00 | 1.88 | 4.98 | 60 |
| Michael Darrell-Hicks | Pirates | 9.7 | 8 | 4 | 7.00 | 1.45 | 4.03 | 60 |
| Orlando Ribalta | Nationals | 24.3 | 25 | 17 | 7.00 | 1.85 | 6.35 | 60 |
| Trevor Richards | Royals | 5.7 | 5 | 2 | 7.00 | 2.29 | 2.39 | 60 |
| Robinson Piña | Marlins | 2.3 | 1 | 1 | 7.00 | 2.57 | 9.11 | 60 |
| Miguel Castro | White Sox | 6.0 | 4 | 5 | 7.00 | 1.67 | 6.43 | 60 |
| Eduarniel Núñez | Athletics | 12.7 | 11 | 11 | 7.00 | 1.89 | 6.02 | 60 |
| Chris Stratton | Royals | 21.0 | 22 | 10 | 7.00 | 2.00 | 4.91 | 60 |
| Carlos Carrasco | Yankees | 45.7 | 34 | 17 | 7.00 | 1.71 | 5.57 | 60 |
| Ryan Rolison | Rockies | 42.1 | 25 | 20 | 7.02 | 1.77 | 6.73 | 60 |
| Isaiah Campbell | Red Sox | 7.2 | 3 | 1 | 7.04 | 1.83 | 4.49 | 60 |
| Angel Chivilli | Rockies | 58.2 | 43 | 23 | 7.06 | 1.69 | 5.71 | 59 |
| Spencer Turnbull | Blue Jays | 6.1 | 4 | 4 | 7.11 | 2.53 | 5.89 | 59 |
| Kendall Graveman | Diamondbacks | 17.2 | 9 | 12 | 7.13 | 1.98 | 5.66 | 59 |
| Josh Walker | Blue Jays | 5.0 | 8 | 2 | 7.20 | 2.00 | 1.10 | 58 |
| Anthony Molina | Rockies | 34.2 | 24 | 6 | 7.27 | 1.67 | 6.78 | 58 |
| Ryan Johnson | Angels | 14.2 | 16 | 5 | 7.36 | 1.98 | 5.56 | 57 |
| Jon Berti | Cubs | 3.2 | 0 | 4 | 7.36 | 2.18 | 6.85 | 57 |
| Kevin Ginkel | Diamondbacks | 25.2 | 29 | 13 | 7.36 | 1.64 | 3.38 | 57 |
| McCade Brown | Rockies | 25.2 | 23 | 17 | 7.36 | 1.83 | 6.39 | 57 |
| Victor Mederos | Angels | 17.0 | 14 | 12 | 7.41 | 1.76 | 6.63 | 57 |
| Tayler Saucedo | Mariners | 13.1 | 12 | 6 | 7.43 | 1.88 | 4.63 | 57 |
| Austin Gomber | Rockies | 57.2 | 34 | 17 | 7.49 | 1.72 | 6.44 | 56 |
| Travis Adams | Twins | 33.2 | 31 | 17 | 7.49 | 1.66 | 5.12 | 56 |
| Sammy Peralta | Angels | 10.2 | 8 | 6 | 7.59 | 1.88 | 3.30 | 55 |
| Ryan Fernandez | Cardinals | 30.1 | 34 | 16 | 7.71 | 1.71 | 5.03 | 54 |
| Luis F. Castillo | Mariners | 7.0 | 5 | 7 | 7.71 | 2.71 | 4.67 | 54 |
| Matt Waldron | Padres | 4.2 | 3 | 6 | 7.71 | 2.57 | 9.05 | 54 |
| Jon Gray | Rangers | 14.0 | 12 | 6 | 7.71 | 1.50 | 7.31 | 54 |
| Sean Hjelle | Giants | 15.0 | 11 | 9 | 7.80 | 2.00 | 5.17 | 54 |
| Chris Roycroft | Cardinals | 20.2 | 15 | 12 | 7.84 | 1.84 | 4.68 | 54 |
| Sam Aldegheri | Angels | 13.2 | 12 | 10 | 7.90 | 2.20 | 6.51 | 53 |
| Allan Winans | Yankees | 9.3 | 6 | 3 | 8.00 | 1.71 | 5.57 | 53 |
| Jordan Romano | Phillies | 42.7 | 47 | 17 | 8.00 | 1.45 | 5.14 | 53 |
| Cam Sanders | Pirates | 6.7 | 4 | 5 | 8.00 | 2.10 | 8.05 | 53 |
| George Soriano | Marlins | 36.7 | 36 | 19 | 8.00 | 1.77 | 6.24 | 53 |
| Richard Lovelady | Mets | 11.7 | 12 | 6 | 8.00 | 1.54 | 5.93 | 53 |
| José Ruiz | Braves | 16.3 | 15 | 9 | 8.00 | 1.96 | 5.30 | 53 |
| Eduardo Salazar | Nationals | 29.0 | 23 | 16 | 8.00 | 2.17 | 6.31 | 53 |
| Connor Gillispie | Marlins | 26.0 | 23 | 11 | 8.00 | 1.65 | 5.60 | 53 |
| Jared Shuster | White Sox | 15.7 | 12 | 5 | 8.00 | 2.04 | 2.53 | 53 |
| Alexis Díaz | Dodgers | 17.7 | 17 | 12 | 8.00 | 1.53 | 7.63 | 53 |
| Austin Cox | Braves | 21.3 | 22 | 7 | 8.00 | 1.73 | 7.51 | 53 |
| Andry Lara | Nationals | 14.3 | 10 | 8 | 8.00 | 2.44 | 5.19 | 53 |
| Scott Effross | Yankees | 10.7 | 6 | 3 | 8.00 | 1.78 | 4.04 | 53 |
| Tanner Houck | Red Sox | 43.2 | 32 | 17 | 8.04 | 1.69 | 5.81 | 52 |
| Jeff Brigham | Diamondbacks | 3.1 | 3 | 1 | 8.10 | 2.40 | 6.33 | 52 |
| Roddery Muñoz | Cardinals | 11.0 | 14 | 9 | 8.18 | 1.64 | 7.74 | 51 |
| Cionel Pérez | Orioles | 21.2 | 21 | 18 | 8.31 | 2.12 | 5.51 | 51 |
| Lazaro Estrada | Blue Jays | 7.1 | 10 | 1 | 8.59 | 1.50 | 4.37 | 49 |
| Roansy Contreras | Rockies | 8.1 | 4 | 1 | 8.64 | 1.20 | 7.30 | 49 |
| Jorge Alcala | Twins | 24.1 | 28 | 15 | 8.88 | 1.81 | 5.34 | 47 |
| Carson Palmquist | Rockies | 34.1 | 27 | 25 | 8.91 | 2.04 | 7.53 | 47 |
| Joey Estes | Athletics | 11.0 | 6 | 6 | 9.00 | 2.00 | 8.37 | 47 |
| Touki Toussaint | Angels | 2.0 | 3 | 1 | 9.00 | 2.50 | 1.60 | 47 |
| Kyle Farmer | Rockies | 1.0 | 0 | 0 | 9.00 | 3.00 | 16.10 | 47 |
| Patrick Monteverde | Marlins | 3.7 | 4 | 1 | 9.00 | 2.73 | 1.74 | 47 |
| Zach Brzykcy | Nationals | 23.0 | 24 | 12 | 9.00 | 1.74 | 5.97 | 47 |
| Gerson Garabito | Rangers | 8.0 | 8 | 1 | 9.00 | 2.00 | 3.10 | 47 |
| Elvin Rodríguez | Brewers | 19.7 | 18 | 7 | 9.00 | 1.68 | 8.29 | 47 |
| Logan Porter | Giants | 1.0 | 0 | 0 | 9.00 | 2.00 | 16.10 | 47 |
| Will Wilson | Guardians | 2.0 | 0 | 0 | 9.00 | 1.00 | 9.60 | 47 |
| Blas Castaño | Mariners | 3.0 | 1 | 2 | 9.00 | 2.00 | 8.77 | 47 |
| Yilber Díaz | Diamondbacks | 3.0 | 1 | 3 | 9.00 | 2.33 | 5.43 | 47 |
| Owen White | White Sox | 7.0 | 6 | 3 | 9.00 | 2.43 | 4.53 | 47 |
| Lucas Gilbreath | Rockies | 1.0 | 2 | 0 | 9.00 | 1.00 | 12.10 | 47 |
| Blade Tidwell | Mets | 15.0 | 10 | 10 | 9.00 | 2.20 | 7.23 | 47 |
| Kyle Nelson | Diamondbacks | 2.0 | 2 | 4 | 9.00 | 2.50 | 13.60 | 47 |
| Jacob Barnes | Blue Jays | 8.0 | 5 | 3 | 9.00 | 1.63 | 4.60 | 47 |
| Reese McGuire | Cubs | 1.0 | 0 | 1 | 9.00 | 3.00 | 19.10 | 47 |
| Tyler Wade | Padres | 1.0 | 0 | 1 | 9.00 | 3.00 | 6.10 | 47 |
| Jesse Chavez | Braves | 8.0 | 8 | 5 | 9.00 | 2.38 | 9.48 | 47 |
| Nate Pearson | Cubs | 14.2 | 7 | 10 | 9.20 | 2.18 | 6.06 | 46 |
| Bradley Blalock | Rockies | 58.2 | 27 | 23 | 9.36 | 1.84 | 7.15 | 45 |
| Luis Peralta | Rockies | 19.0 | 16 | 18 | 9.47 | 2.32 | 8.36 | 44 |
| Anthony Misiewicz | Twins | 4.2 | 5 | 4 | 9.64 | 1.93 | 9.77 | 44 |
| Casey Lawrence | Blue Jays | 2.2 | 1 | 0 | 10.13 | 2.25 | 2.19 | 41 |
| Robert Stock | Red Sox | 2.2 | 1 | 4 | 10.13 | 3.00 | 13.55 | 41 |
| Shaun Anderson | Angels | 11.1 | 11 | 3 | 10.32 | 2.03 | 8.96 | 41 |
| Joe La Sorsa | Reds | 6.2 | 2 | 2 | 10.80 | 2.25 | 11.81 | 39 |
| Tyler Zuber | Mets | 12.0 | 14 | 6 | 11.00 | 1.92 | 5.52 | 38 |
| J.P. Feyereisen | Dodgers | 4.0 | 4 | 1 | 11.00 | 3.00 | 8.35 | 38 |
| Mason Thompson | Nationals | 10.7 | 11 | 12 | 11.00 | 2.63 | 5.63 | 38 |
| Wander Suero | Braves | 6.3 | 7 | 4 | 11.00 | 2.21 | 8.95 | 38 |
| Tanner Rainey | Pirates | 9.7 | 11 | 9 | 11.00 | 1.76 | 3.62 | 38 |
| Luarbert Arias | Marlins | 10.3 | 10 | 5 | 11.00 | 2.13 | 5.13 | 38 |
| Triston McKenzie | Guardians | 5.2 | 4 | 7 | 11.12 | 2.47 | 8.10 | 38 |
| Brooks Kriske | Twins | 12.0 | 14 | 10 | 11.25 | 2.33 | 4.35 | 37 |
| Ian Anderson | Angels | 9.1 | 8 | 7 | 11.57 | 2.57 | 6.51 | 36 |
| Colin Poche | Nationals | 9.3 | 11 | 14 | 12.00 | 2.79 | 6.64 | 35 |
| Anthony Maldonado | Athletics | 6.0 | 7 | 5 | 12.00 | 2.50 | 9.77 | 35 |
| Ryan Loutos | Nationals | 12.0 | 8 | 8 | 12.00 | 2.33 | 8.10 | 35 |
| Rolddy Muñoz | Braves | 3.7 | 5 | 5 | 12.00 | 2.45 | 8.00 | 35 |
| Miguel Rojas | Dodgers | 5.0 | 0 | 2 | 12.00 | 2.60 | 12.10 | 35 |
| Bobby Miller | Dodgers | 5.0 | 7 | 2 | 12.00 | 2.60 | 6.70 | 35 |
| Troy Taylor | Mariners | 6.2 | 2 | 3 | 12.15 | 2.55 | 8.10 | 35 |
| Eli Morgan | Cubs | 7.1 | 4 | 3 | 12.27 | 2.05 | 8.73 | 34 |
| Didier Fuentes | Braves | 13.0 | 12 | 6 | 13.00 | 2.23 | 8.64 | 32 |
| Vidal Bruján | Braves | 2.0 | 0 | 1 | 13.00 | 2.50 | 11.10 | 32 |
| Forrest Whitley | Astros | 12.0 | 12 | 8 | 13.00 | 2.25 | 6.35 | 32 |
| Michel Otañez | Athletics | 5.3 | 6 | 5 | 13.00 | 2.25 | 8.54 | 32 |
| Lucas Sims | Nationals | 12.3 | 13 | 14 | 13.00 | 2.27 | 6.51 | 32 |
| Noah Murdock | Athletics | 17.0 | 21 | 20 | 13.00 | 2.71 | 4.16 | 32 |
| Alex Carrillo | Mets | 4.7 | 4 | 2 | 13.00 | 1.71 | 13.81 | 32 |
| Andrew Walters | Guardians | 1.1 | 2 | 0 | 13.50 | 1.50 | 11.28 | 31 |
| Cody Bolton | Guardians | 2.0 | 1 | 0 | 13.50 | 2.00 | 2.10 | 31 |
| Doug Nikhazy | Guardians | 4.0 | 5 | 6 | 13.50 | 2.75 | 5.10 | 31 |
| Tucker Barnhart | Rangers | 2.0 | 0 | 0 | 13.50 | 2.50 | 3.10 | 31 |
| Rowdy Tellez | Rangers | 2.0 | 0 | 0 | 13.50 | 2.50 | 9.60 | 31 |
| Jordan Weems | Astros | 4.3 | 0 | 3 | 14.00 | 2.77 | 5.18 | 30 |
| Zach Pop | Mets | 6.7 | 3 | 2 | 14.00 | 2.55 | 10.90 | 30 |
| Carson Ragsdale | Orioles | 5.0 | 4 | 1 | 14.40 | 2.20 | 4.70 | 29 |
| Thomas Harrington | Pirates | 8.7 | 7 | 7 | 15.00 | 2.88 | 8.41 | 28 |
| Enrique Hernández | Dodgers | 5.3 | 1 | 8 | 15.00 | 3.56 | 9.67 | 28 |
| Jonah Bride | Marlins | 6.0 | 2 | 3 | 15.00 | 2.83 | 6.10 | 28 |
| Michael Mercado | Phillies | 3.0 | 4 | 4 | 15.00 | 3.67 | 8.77 | 28 |
| Erik Swanson | Blue Jays | 5.1 | 3 | 5 | 15.19 | 2.44 | 9.96 | 28 |
| Chayce McDermott | Orioles | 8.2 | 9 | 12 | 15.58 | 2.77 | 10.05 | 27 |
| Joe Mantiply | Diamondbacks | 9.2 | 8 | 3 | 15.83 | 3.00 | 9.40 | 27 |
| Javier Sanoja | Marlins | 9.3 | 1 | 5 | 16.00 | 3.11 | 10.07 | 26 |
| Jose Corniell | Rangers | 1.2 | 1 | 1 | 16.20 | 2.40 | 14.77 | 26 |
| Kyle Gibson | Orioles | 12.1 | 10 | 7 | 16.78 | 2.92 | 10.70 | 25 |
| Cody Poteet | Orioles | 2.2 | 1 | 2 | 16.88 | 3.00 | 4.92 | 25 |
| Kody Clemens | Phillies | 1.0 | 0 | 0 | 18.00 | 3.00 | 29.10 | 23 |
| Drew Sommers | Tigers | 3.0 | 3 | 3 | 18.00 | 3.33 | 8.43 | 23 |
| Jake Palisch | White Sox | 1.0 | 0 | 0 | 18.00 | 3.00 | 3.10 | 23 |
| Abraham Toro | Red Sox | 1.0 | 0 | 1 | 18.00 | 5.00 | 6.10 | 23 |
| Ali Sánchez | Blue Jays | 1.0 | 1 | 0 | 18.00 | 3.00 | 1.10 | 23 |
| Mike Yastrzemski | Royals | 1.0 | 0 | 1 | 18.00 | 3.00 | 6.10 | 23 |
| Travis Jankowski | Mets | 1.0 | 0 | 1 | 18.00 | 3.00 | 6.10 | 23 |
| Noah Davis | Dodgers | 11.0 | 15 | 6 | 18.00 | 2.55 | 10.28 | 23 |
| Chase Petty | Reds | 6.0 | 7 | 8 | 19.50 | 3.67 | 11.27 | 22 |
| Connor Thomas | Brewers | 5.3 | 5 | 2 | 20.00 | 2.63 | 9.67 | 21 |
| Geoff Hartlieb | Tigers | 3.3 | 5 | 6 | 21.00 | 4.20 | 13.31 | 20 |
| Jhonny Pereda | Athletics | 3.0 | 3 | 2 | 21.00 | 3.67 | 7.43 | 20 |
| Nathan Wiles | Braves | 1.0 | 1 | 0 | 27.00 | 4.00 | 1.10 | 16 |
| Pablo Reyes | Yankees | 1.0 | 0 | 0 | 27.00 | 5.00 | 16.10 | 16 |
| Cole Wilcox | Rays | 1.0 | 1 | 3 | 27.00 | 7.00 | 10.10 | 16 |
| Nolan Hoffman | Phillies | 1.0 | 2 | 1 | 27.00 | 4.00 | 2.10 | 16 |
| Alex Jackson | Orioles | 1.0 | 0 | 2 | 27.00 | 5.00 | 9.10 | 16 |
| Oswald Peraza | Yankees | 2.3 | 0 | 0 | 30.00 | 3.86 | 8.68 | 14 |
| Tyler Heineman | Blue Jays | 3.1 | 0 | 0 | 32.40 | 4.50 | 7.29 | 13 |
| Cooper Hummel | Astros | 1.0 | 0 | 0 | 36.00 | 5.00 | 16.10 | 12 |
| Scott Kingery | Angels | 2.0 | 1 | 0 | 36.00 | 6.00 | 15.10 | 12 |
| Gary Sánchez | Orioles | 1.0 | 0 | 1 | 36.00 | 3.00 | 19.10 | 12 |
| Amed Rosario | Nationals | 1.0 | 0 | 2 | 36.00 | 7.00 | 22.10 | 12 |
| Jorge Mateo | Orioles | 1.0 | 0 | 2 | 45.00 | 7.00 | 22.10 | 9 |
| José Caballero | Yankees | 1.0 | 0 | 1 | 54.00 | 6.00 | 32.10 | 8 |
| Austin Nola | Rockies | 1.0 | 0 | 0 | 72.00 | 8.00 | 29.10 | 6 |
| Emmanuel Rivera | Orioles | 1.0 | 0 | 2 | 72.00 | 10.00 | 22.10 | 6 |